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Human Claudin-11 ELISA Kit (Chemiluminescence)

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ELISA: Human Claudin-11 ELISA Kit (Chemiluminescence) [NBP2-75325] - Samples were spiked with high concentrations of Human Claudin-11 and diluted with Reference Standard & Sample Diluent to produce samples with values ...read more
ELISA: Human Claudin-11 ELISA Kit (Chemiluminescence) [NBP2-75325] - Standard Curve Reference

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Suitable Sample Type
Serum, plasma and other biological fluids
Standard Curve Range
31.25-2000 pg/mL
Sensitivity
18.75 pg/mL

Order Details

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Human Claudin-11 ELISA Kit (Chemiluminescence) Summary

Specificity
This kit recognizes Human CLDN11 in samples. No significant cross-reactivity or interference between Human CLDN11 and analogues was observed.
Standard Curve Range
31.25-2000 pg/mL
Sensitivity
18.75 pg/mL
Assay Type
Sandwich-CLIA
Inter-Assay
CV% < 11.29%
Intra-Assay
CV% < 10.23%
Spike Recovery
87-114%
Sample Volume
100 uL
Kit Type
ELISA Kit (Chemiluminescence)
Gene
CLDN11

Applications/Dilutions

Dilutions
  • ELISA

Packaging, Storage & Formulations

Storage
Storage of components varies. See protocol for specific instructions.

Kit Components

Components
  1. Biotinylated Detection Ab Diluent
  2. Concentrated Biotinylated Detection Ab (100x)
  3. Concentrated HRP Conjugate (100x)
  4. Concentrated Wash Buffer (25x)
  5. HRP Conjugate Diluent
  6. Micro CLIA Plate (Dismountable)
  7. Plate Sealer
  8. Product Manual
  9. Reference Standard
  10. Sample Diluent
  11. Substrate Reagent A
  12. Substrate Reagent B

Alternate Names for Human Claudin-11 ELISA Kit (Chemiluminescence)

  • claudin 11
  • Claudin11
  • Claudin-11
  • CLDN11
  • Oligodendrocyte-specific protein
  • OSP
  • OSPOTMoligodendrocyte transmembrane protein
  • OTM

Background

Oligodendrocyte specific protein belongs is a major component of central nervous system myelin that is necessary for normal CNS function. The claudin superfamily consists of many structurally related proteins in humans. These proteins, which include claudin 1 through 18, and are located in both epithelial and endothelial cells in all tight junction bearing tissues. Claudins, which consist of four transmembrane domains and two extracellular loops, make up tight junction strands. There is growing evidence that the Claudin 11 protein determines the permeability between layers of myelin sheaths via focal adhesion and with its expression highly regulated during development, may play an important role in cellular proliferation and migration. In addition, the protein is a candidate autoantigen in the development of autoimmune demyelinating disease.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

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Bioinformatics

Gene Symbol CLDN11