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Clathrin Heavy Chain 1/CHC17 Antibody (CHC/1432) [DyLight 594]

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Product Details

Summary
Reactivity Hu, Mu, Rt, Po, Av, Bv, Ca, Pm, XpSpecies Glossary
Applications ICC/IF
Clone
CHC/1432
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 594

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP3-08333AF350
Alexa Fluor 405
NBP3-08333AF405
Alexa Fluor 488
NBP3-08333AF488
Alexa Fluor 532
NBP3-08333AF532
Alexa Fluor 594
NBP3-08333AF594
Alexa Fluor 647
NBP3-08333AF647
Alexa Fluor 700
NBP3-08333AF700
Alexa Fluor 750
NBP3-08333AF750
Allophycocyanin
NBP3-08333APC
Biotin
NBP3-08333B
CoraFluor 1
NBP3-08333CL1
DyLight 350
NBP3-08333UV
DyLight 405
NBP3-08333V
DyLight 488
NBP3-08333G
DyLight 550
NBP3-08333R
DyLight 650
NBP3-08333C
DyLight 680
NBP3-08333FR
DyLight 755
NBP3-08333IR
FITC
NBP3-08333F
HRP
NBP3-08333H
Janelia Fluor 525
NBP3-08333JF525
Janelia Fluor 549
NBP3-08333JF549
Janelia Fluor 646
NBP3-08333JF646
Janelia Fluor 669
NBP3-08333JF669
PE
NBP3-08333PE
PerCP
NBP3-08333PCP
Unconjugated
NBP3-07569-100ug
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP3-07569-100ug
Azide and BSA Free
NBP3-08333
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Clathrin Heavy Chain 1/CHC17 Antibody (CHC/1432) [DyLight 594] Summary

Immunogen
Recombinant full-length human Clathrin Heavy Chain 1/CHC17 protein
Localization
Cytoplasmic
Specificity
Recognizes protein of 192kDa, which is identified as Clathrin Heavy Chain. Clathrin is composed of three heavy chains and three light chains, which associate non-covalently to form a triskelion structure. Clathrin heavy chain (HC) is composed of a terminal globular domain, a distal segment and a proximal segment containing a light chain-binding site. The proximal segment of the Clathrin HC protein is essential for interactions between Clathrin heavy chains and light chains, which result in the formation of the triskelion structure.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
CLTC
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

African Green Monkey

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Clathrin Heavy Chain 1/CHC17 Antibody (CHC/1432) [DyLight 594]

  • CHC
  • CHC17
  • Clathrin Heavy Chain 1
  • Clathrin heavy chain on chromosome 17
  • clathrin, heavy chain (Hc)
  • clathrin, heavy chain
  • clathrin, heavy polypeptide (Hc)
  • clathrin, heavy polypeptide-like 2
  • CLH17
  • CLH-17
  • CLTC
  • CLTCL2
  • Hc
  • KIAA0034

Background

Clathrin is a major protein component of the cytoplasmic face of intracellular organelles, called coated vesicles and coated pits. These specialized organelles are involved in the intracellular trafficking of receptors and endocytosis of a variety of macromolecules. The basic subunit of the clathrin coat is composed of three heavy chains (192 kDa) and three light chains (LCa or LCb, 25-29 kDa) and self assembles into a polyhedral cytoskeletal element. Self assembly facilitates clathrin's central role in membrane sorting and selective transport within the cell.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

ICC/IF Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol CLTC