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Chromogranin A Antibody (CGA/413) [DyLight 405]

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Product Details

Summary
Reactivity Hu, Rt(-)Species Glossary
Applications IHC, MA
Clone
CGA/413
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 405

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-47850AF350
Alexa Fluor 405
NBP2-47850AF405
Alexa Fluor 488
NBP2-47850AF488
Alexa Fluor 532
NBP2-47850AF532
Alexa Fluor 594
NBP2-47850AF594
Alexa Fluor 647
NBP2-47850AF647
Alexa Fluor 700
NBP2-47850AF700
Alexa Fluor 750
NBP2-47850AF750
Biotin
NBP2-47850B
DyLight 350
NBP2-47850UV
DyLight 488
NBP2-47850G
DyLight 550
NBP2-47850R
DyLight 594
NBP2-47850DL594
DyLight 650
NBP2-47850C
DyLight 680
NBP2-47850FR
DyLight 755
NBP2-47850IR
FITC
NBP2-47850F
HRP
NBP2-47850H
Janelia Fluor 549
NBP2-47850JF549
Janelia Fluor 646
NBP2-47850JF646
Unconjugated
NBP2-44776-0.1mg
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-44776-0.1mg
Azide and BSA Free
NBP2-47850-0.1mg
IHC-Prediluted
NBP2-48081
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Chromogranin A Antibody (CGA/413) [DyLight 405] Summary

Description
This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
Immunogen
Recombinant full-length human Chromogranin A protein (Uniprot: P10645)
Localization
Finely granular cytoplasmic
Marker
Neuroendocrine Marker
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
CHGA
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Microarray
  • Protein Array
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Does not react with Rat.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Chromogranin A Antibody (CGA/413) [DyLight 405]

  • betagranin (N-terminal fragment of chromogranin A)
  • Betagranin
  • Catestatin
  • CGA
  • CHGA
  • Chromofungin
  • chromogranin A (parathyroid secretory protein 1)
  • Chromogranin A
  • chromogranin-A
  • Pancreastatin
  • Parastatin
  • Parathyroid Secretory Protein 1
  • Pituitary Secretory Protein I
  • SP-I

Background

Chromogranin A (CgA) is an 86 kDa protein that is the major member of the granin family of acidic secretory glycoproteins located in neuroendocrine cells. CgA is believed to play a role in targeting peptide hormones and neurotransmitters to granules of the regulated pathways and inhibit hormone and neurotransmitter release. Also, the widespread distribution of CgA has made the measurement of circulating immunoreactive CgA a valuable tool in the diagnosis of neuroendocrine neoplasia, and CgA immunohistochemistry can help to identify the neuroendocrine nature of tumors. The N-terminal domain of CgA inhibits tumor necrosis factor a (TNFa) induced gap formation in human umbilical venous endothelial cells. CgA levels which reflect neuroendocrine differentiation of prostatic carcinoma may have a diagnostic, therapeutic and prognostic role in the management of prostate cancer patients.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs for Chromogranin A Antibody (NBP2-47850V). (Showing 1 - 1 of 1 FAQ).

  1. I have following question about antibodies against Chromogranin A. Your products list the species but canine is not included. Does it mean that the products cannot be used on canine tissues?
    • When we do not list a species, it means we have not tested an antibody to work with those samples. If we test an antibody and find that it does not work, we will list the species with a minus sign. Unfortunately, we haven't tried these abs on canine tissues and they may work, but we cannot guarantee it. If you would like to purchase one to try, you will be eligible for the Innovators Reward Program.

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CHGA