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Chromogranin A Antibody (CGA/413 + CHGA/777 + CHGA/798) [DyLight 594]

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Product Details

Summary
Reactivity Hu, Mu, Rt, Po, PmSpecies Glossary
Applications IHC
Clone
CGA/413 + CHGA/777 + CHGA/798
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 594

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-47846AF350
Alexa Fluor 405
NBP2-47846AF405
Alexa Fluor 488
NBP2-47846AF488
Alexa Fluor 532
NBP2-47846AF532
Alexa Fluor 594
NBP2-47846AF594
Alexa Fluor 647
NBP2-47846AF647
Alexa Fluor 700
NBP2-47846AF700
Alexa Fluor 750
NBP2-47846AF750
Biotin
NBP2-47846B
CoraFluor 1
NBP2-47846CL1
DyLight 350
NBP2-47846UV
DyLight 405
NBP2-47846V
DyLight 488
NBP2-47846G
DyLight 550
NBP2-47846R
DyLight 650
NBP2-47846C
DyLight 680
NBP2-47846FR
DyLight 755
NBP2-47846IR
FITC
NBP2-47846F
HRP
NBP2-47846H
Janelia Fluor 525
NBP2-47846JF525
Janelia Fluor 549
NBP2-47846JF549
Janelia Fluor 585
NBP2-47846JF585
Janelia Fluor 635
NBP2-47846JF635
Janelia Fluor 646
NBP2-47846JF646
Janelia Fluor 669
NBP2-47846JF669
Unconjugated
NBP2-44764-0.1mg
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-44764-0.1mg
Azide and BSA Free
NBP2-47846-0.1mg
IHC-Prediluted
NBP2-48063
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Chromogranin A Antibody (CGA/413 + CHGA/777 + CHGA/798) [DyLight 594] Summary

Immunogen
Recombinant human Chromogranin A protein (Uniprot: P10645)
Localization
Finely granular cytoplasmic
Marker
Neuroendocrine Marker
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
CHGA
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Chromogranin A Antibody (CGA/413 + CHGA/777 + CHGA/798) [DyLight 594]

  • betagranin (N-terminal fragment of chromogranin A)
  • Betagranin
  • Catestatin
  • CGA
  • CHGA
  • Chromofungin
  • chromogranin A (parathyroid secretory protein 1)
  • Chromogranin A
  • chromogranin-A
  • Pancreastatin
  • Parastatin
  • Parathyroid Secretory Protein 1
  • Pituitary Secretory Protein I
  • SP-I

Background

Chromogranin A (CgA) is an 86 kDa protein that is the major member of the granin family of acidic secretory glycoproteins located in neuroendocrine cells. CgA is believed to play a role in targeting peptide hormones and neurotransmitters to granules of the regulated pathways and inhibit hormone and neurotransmitter release. Also, the widespread distribution of CgA has made the measurement of circulating immunoreactive CgA a valuable tool in the diagnosis of neuroendocrine neoplasia, and CgA immunohistochemistry can help to identify the neuroendocrine nature of tumors. The N-terminal domain of CgA inhibits tumor necrosis factor a (TNFa) induced gap formation in human umbilical venous endothelial cells. CgA levels which reflect neuroendocrine differentiation of prostatic carcinoma may have a diagnostic, therapeutic and prognostic role in the management of prostate cancer patients.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Chromogranin A Antibody (NBP2-47846DL594) (0)

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FAQs for Chromogranin A Antibody (NBP2-47846DL594). (Showing 1 - 1 of 1 FAQ).

  1. I have following question about antibodies against Chromogranin A. Your products list the species but canine is not included. Does it mean that the products cannot be used on canine tissues?
    • When we do not list a species, it means we have not tested an antibody to work with those samples. If we test an antibody and find that it does not work, we will list the species with a minus sign. Unfortunately, we haven't tried these abs on canine tissues and they may work, but we cannot guarantee it. If you would like to purchase one to try, you will be eligible for the Innovators Reward Program.

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Bioinformatics

Gene Symbol CHGA