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ChemR23/CMKLR1 Antibody (477806) [Alexa Fluor® 488]

Images

 
RAW 264.7 mouse monocyte/macrophage cell line was stained with Rat Anti-Mouse ChemR23 Alexa Fluor® 488-conjugated Monoclonal Antibody (Catalog # FAB7610G, filled histogram) or isotype control antibody (IC013G, open ...read more
HEK293 cells transfected with Human ChemR23 were stained with Rat Anti-Mouse ChemR23 Alexa Fluor® 488‑conjugated Monoclonal Antibody (Catalog # FAB7610G, filled histogram) or isotype control antibody ...read more

Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow
Clone
477806
Clonality
Monoclonal
Host
Rat
Conjugate
Alexa Fluor 488

Order Details

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ChemR23/CMKLR1 Antibody (477806) [Alexa Fluor® 488] Summary

Immunogen
NS0 mouse myeloma cell line transfected with mouse ChemR23
Specificity
Detects mouse ChemR23 in flow cytometry.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Rat
Gene
CMKLR1
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 5 uL/10^6 cells

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8° C. Do not use past expiration date. Protect from light.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes


This product is provided under an agreement between Life Technologies Corporation and R&D Systems, Inc, and the manufacture, use, sale or import of this product is subject to one or more US patents and corresponding non-US equivalents, owned by Life Technologies Corporation and its affiliates. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components (1) in manufacturing; (2) to provide a service, information, or data to an unaffiliated third party for payment; (3) for therapeutic, diagnostic or prophylactic purposes; (4) to resell, sell, or otherwise transfer this product or its components to any third party, or for any other commercial purpose. Life Technologies Corporation will not assert a claim against the buyer of the infringement of the above patents based on the manufacture, use or sale of a commercial product developed in research by the buyer in which this product or its components was employed, provided that neither this product nor any of its components was used in the manufacture of such product. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, Cell Analysis Business Unit, Business Development, 29851 Willow Creek Road, Eugene, OR 97402, Tel: (541) 465-8300. Fax: (541) 335-0354.

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for ChemR23/CMKLR1 Antibody (477806) [Alexa Fluor® 488]

  • CHEMERINR
  • chemokine receptor-like 1
  • chemokine-like receptor 1
  • ChemR23
  • cmklr1
  • Dez
  • Gpcr27
  • G-protein coupled receptor ChemR23
  • G-protein coupled receptor DEZ
  • MGC126105
  • MGC126106
  • orphan G-protein coupled receptor, Dez

Background

ChemR23 is a chemoattractant receptor expressed on dendritic cells and inflammatory M1 macrophages. ChemR23 binds Chemerin and Resolvin E1 (a lipid mediator), and promotes inflammation resolution. ChemR23 also functions as a coreceptor for SIV and some primary HIV-1 strains (1,2). Mouse and human ChemR23 share 80% amino acid sequence identity.
  1. Samson, M. et al. (1998) Eur. J. Immunol. 28:1689.
  2. Herova, M. et al. (2015) J. Immunol. 194:2330.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol CMKLR1