CDX2 Antibody - BSA Free

CDX2 is a member of the caudal homeobox family of transcription factors that also includes the proteins CDX1 and CDX4. CDX2 is strongly expressed in the trophectoderm in the blastocyst with expression maintained within the proliferating extra-embryonic ectoderm during development. It is required for the repression of the transcription of the POU5F1/Oct4 and NANOG genes in the outer cells of the blastocyst and is thus essential for the segregation of the inner cell mass and trophectoderm at the blastocyst stage. Aberrant expression of CDX2 is associated with numerous types of carcinomas, including intestinal metaplasia, gastric carcinoma, and acute myeloid leukemia due to deregulated HOX gene expression.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publication using NBP1-77113	Applications	Species
He H, Zhang H, Li Q et al. Low oxygen concentrations improve yak oocyte maturation and enhance the developmental competence of preimplantation embryos Theriogenology 2020-06-28 [PMID: 32673901]

Array NBP1-77113

• CDX2 Antibodies
• CDX2 ELISA Kits
• CDX2 Lysate
• CDX2 Proteins
• CDX2 ELISA