CD94 Antibody (18D3) - Azide and BSA Free Summary
Immunogen |
CHO cells transfected with the B6 allele of CD94 |
Specificity |
Mouse CD94 receptor subunit, Mr 70 kDa |
Isotype |
IgG2a Kappa |
Clonality |
Monoclonal |
Host |
Rat |
Gene |
KLRD1 |
Purity |
Protein A or G purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Flow Cytometry 1 ug/10^6 cells
|
Reactivity Notes
Packaging, Storage & Formulations
Storage |
Store at 4C. Do not freeze. |
Buffer |
0.1M BBS (pH 8.2) |
Preservative |
No Preservative |
Concentration |
0.5 mg/ml |
Purity |
Protein A or G purified |
Alternate Names for CD94 Antibody (18D3) - Azide and BSA Free
Background
The monoclonal antibody 18D3 reacts with the mouse CD94 receptor subunit, a 70kDa type II transmembrane glycoprotein. CD94 is expressed on the surface of NK cells, NK T cells and some memory phenotype CD8+ cells. (2) When CD94 is paired with NKG2A, C, or E subunit, it binds the nonclassical MHC class Ib molecule Qa-1b and results in a CD94 high population by flow cytometry. (1, 2) Approximately half of NK cells do not express NKG2A, C or E; these cells express CD94 on the surface in a form that does not bind Qa-1b and is believed to be nonfunctional, producing a CD94 low population by flow cytometry. (1, 2) CD94 is thought to play a role in the adhesion and activation of the NK cell lineage.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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