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CD94 Antibody (18D3) - Azide and BSA Free

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Flow Cytometry: CD94 Antibody (18D3) [NBP1-28119] - C57BL/6 mouse splenocytes were stained with Rat Anti-Mouse CD94-BIOT (SB Cat. 1809-08) and Mouse Anti-Mouse NK1.1-PE (SB Cat. No. 1805-09) followed by ...read more

Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow
Clone
18D3
Clonality
Monoclonal
Host
Rat
Conjugate
Unconjugated
Format
Azide and BSA Free
Concentration
0.5 mg/ml

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CD94 Antibody (18D3) - Azide and BSA Free Summary

Immunogen
CHO cells transfected with the B6 allele of CD94
Specificity
Mouse CD94 receptor subunit, Mr 70 kDa
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Rat
Gene
KLRD1
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry 1 ug/10^6 cells

Reactivity Notes

Mouse.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
0.1M BBS (pH 8.2)
Preservative
No Preservative
Concentration
0.5 mg/ml
Purity
Protein A or G purified

Alternate Names for CD94 Antibody (18D3) - Azide and BSA Free

  • CD94 antigen
  • CD94
  • CD94natural killer cells antigen CD94
  • Killer cell lectin-like receptor subfamily D member 1
  • killer cell lectin-like receptor subfamily D, member 1
  • KLRD1
  • KP43
  • NK cell receptor

Background

The monoclonal antibody 18D3 reacts with the mouse CD94 receptor subunit, a 70kDa type II transmembrane glycoprotein. CD94 is expressed on the surface of NK cells, NK T cells and some memory phenotype CD8+ cells. (2) When CD94 is paired with NKG2A, C, or E subunit, it binds the nonclassical MHC class Ib molecule Qa-1b and results in a CD94 high population by flow cytometry. (1, 2) Approximately half of NK cells do not express NKG2A, C or E; these cells express CD94 on the surface in a form that does not bind Qa-1b and is believed to be nonfunctional, producing a CD94 low population by flow cytometry. (1, 2) CD94 is thought to play a role in the adhesion and activation of the NK cell lineage.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol KLRD1