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CD39L1/ENTPD2 Antibody

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Western blot shows lysates of human heart tissue. PVDF Membrane was probed with 1 µg/mL of Human CD39L1/ENTPD2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF6087) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # HAF016). A specific band was detected for CD39L1/ENTPD2 at approximately 70 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 8.
Western blot shows lysates of human heart tissue. PVDF Membrane was probed with 1 µg/mL of Human CD39L1/ENTPD2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF6087) followed by HRP-conjugated Anti-Sheep IgG ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IP
Clonality
Polyclonal
Host
Sheep
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

View Available Formulations
Catalog# & Formulation Size Price
Carrier Free
AF6087-SP
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CD39L1/ENTPD2 Antibody Summary

Immunogen
Chinese hamster ovary cell line CHO-derived recombinant human CD39L1/ENTPD2
Thr29-Asp460
Accession # Q9Y5L3
Specificity
Detects human CD39L1 in direct ELISAs and Western blots.  In direct ELISAs, approximately 40% cross-reactivity with recombinant mouse CD39L1 and less than 1% cross-reactivity with recombinant human (rh) CD39L2, rhCD39L3, and rhCD39L4 is observed.
Source
N/A
Isotype
IgG
Clonality
Polyclonal
Host
Sheep
Gene
ENTPD2
Purity Statement
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Immunoprecipitation 25 ug/mL
  • Western Blot 1 ug/mL
Publications
Read Publication using AF6087.

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Sterile PBS to a final concentration of 0.2 mg/mL.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CD39L1/ENTPD2 Antibody

  • CD39 antigen-like 1
  • CD39L1
  • CD39L1NTPDase 2
  • CD39-like-1
  • EC 3.6.1
  • EC 3.6.1.-
  • EC 3.6.1.5
  • Ecto-ATP diphosphohydrolase 2
  • Ecto-ATPase 2
  • Ecto-ATPase
  • Ecto-ATPDase 2
  • ectonucleoside triphosphate diphosphohydrolase 2
  • ENTPD2
  • NTPD2
  • NTPDase 2
  • NTPDase-2

Background

CD39L1, also known as ENTPD2 and NTPDase2, is an ectonucleotidase belonging to the CD39 family. It is found on the surface of vascular adventitial cells and accessory vascular cells (1). CD39L1 is a Ca2+ and Mg2+ dependent enzyme that activates platelets by preferentially converting ATP to ADP (2). CD39L1 plays a role in regulating thrombosis and inflammation (3). It is considered to be a therapeutic target for thromboregulation and the treatment of vascular inflammation (2, 4).

  1. Zimmermann, H. et al. 2000 Proceedings of the Second International Workshop on EctoATPases and Related Ectonucleotidases:18.
  2. Robson, S.C. et al. 2001 Drug Dev. Res. 53:193.
  3. Marcus, A.J. et al. 2005 Semin. Thromb. Hemost. 31:234.
  4. Sevigny, J. et al. 2002 Blood 99:2801.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol ENTPD2
Uniprot