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Cathepsin D Antibody

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Western Blot: Cathepsin D Antibody [NBP1-85562] - Analysis in human cell line SK-BR-3.
Western Blot: Cathepsin D Antibody [NBP1-85562] - Analysis in human cell line SK-BR-3.
Immunohistochemistry-Paraffin: Cathepsin D Antibody [NBP1-85562] - Staining of human small intestine shows moderate to strong granular cytoplasmic positivity in glandular and lymphoid cells.
Immunohistochemistry-Paraffin: Cathepsin D Antibody [NBP1-85562] - Staining of human skeletal muscle shows occasional granular cytoplasmic positivity in a subset of myocytes.
Immunohistochemistry-Paraffin: Cathepsin D Antibody [NBP1-85562] - Staining of human fallopian tube shows moderate granular cytoplasmic positivity in glandular cells.
Immunohistochemistry-Paraffin: Cathepsin D Antibody [NBP1-85562] - Staining of human cerebral cortex shows strong granular cytoplasmic positivity in neurons.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

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Cathepsin D Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: LWVPSIHCKLLDIACWIHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQVFGEATKQPGITFIAAKFDGILGMAYPRISVNNVLPVFDNLMQQKLVDQNIFSFYLSRDPDAQPGGELMLGGT
Marker
Lysosomes Marker
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CTSD
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:1000 - 1:2500
  • Immunohistochemistry-Paraffin 1:1000 - 1:2500
  • Western Blot 0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
Cathepsin D Protein (NBP1-85562PEP)
Publications
Read Publications using NBP1-85562.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (86%), Rat (86%)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Cathepsin D Antibody

  • cathepsin D (lysosomal aspartyl protease)
  • Cathepsin D
  • CPSD
  • CTSD
  • EC 3.4.23
  • EC 3.4.23.5
  • lysosomal aspartyl peptidase
  • lysosomal aspartyl protease
  • MGC2311
  • neuronal 10

Background

Cathepsin D has been reported to be involved in malignant tumour progression and with prognosis of various human cancers.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Cathepsin D Antibody (NBP1-85562)(2)


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Secondary Antibodies

 

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Bioinformatics

Gene Symbol CTSD