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Calcitonin R Antibody

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Immunohistochemistry-Paraffin: Calcitonin R Antibody [NBP2-68772] - Staining of human hypothalamus using Anti-CALCR antibody.
Immunohistochemistry-Paraffin: Calcitonin R Antibody [NBP2-68772] - Staining of human hypothalamus using Anti-CALCR antibody.
Independent Antibodies: Immunohistochemistry-Paraffin: Calcitonin R Antibody [NBP2-68772] - Staining of human cerebral cortex, colon, hypothalamus and testis using Anti-CALCR antibody NBP2-68772 (A) shows similar ...read more
Immunohistochemistry-Paraffin: Calcitonin R Antibody [NBP2-68772] - Staining of human colon.
Immunohistochemistry-Paraffin: Calcitonin R Antibody [NBP2-68772] - Staining of human cerebral cortex.
Immunohistochemistry-Paraffin: Calcitonin R Antibody [NBP2-68772] - Staining of human testis.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
 

Independent Antibodies

        

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Calcitonin R Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to amino acids: AEAGDIPIYICHQELRNEPANNQGEESAEIIPLNIIEQES
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CALCR
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:500 - 1:1000
  • Immunohistochemistry-Paraffin 1:500 - 1:1000
Application Notes
Recommended conditions for IHC,Retrieval method: HIER pH6
Control Peptide
Calcitonin R Recombinant Protein Antigen (NBP2-68772PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Protein A purified

Alternate Names for Calcitonin R Antibody

  • Calcitonin R
  • calcitonin receptor
  • CalcitoninR
  • CALCR
  • CRT
  • CTR
  • CT-R
  • CTR1

Background

The Calcitonin Receptor inhibits bone resorption. This receptor is expressed during development and is involved in morphogenesis. Three alternatively spliced Calcitonin Receptor isoforms have been identified. In addition to binding calcitonin, the Calcitonin Receptor can complex with RAMP3 (receptor activity modifying protein) to bind amylin, which regulates pancreatic islet function and is involved in Type II diabetes. The Calcitonin Receptor has been reported in artery, blood, bone, brain, kidney, lung, placenta, prostate, skeletal muscle, and thyroid. ESTs have been isolated from bone, embryo, kidney, and melanocyte/uterus/fetal heart libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol CALCR