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Cadherin-17 Antibody (141713) [Unconjugated]

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Western blot shows lysates of human colon tissue. PVDF membrane was probed with 1 µg/mL of Mouse Anti-Human Cadherin-17 Monoclonal Antibody (Catalog # MAB1032) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF018). A specific band was detected for Cadherin-17 at approximately 125 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.
Western blot shows lysates of human colon tissue. PVDF membrane was probed with 1 µg/mL of Mouse Anti-Human Cadherin-17 Monoclonal Antibody (Catalog # MAB1032) followed by HRP-conjugated Anti-Mouse IgG Secondary ...read more
Cadherin‑17 was detected in immersion fixed paraffin-embedded sections of human ascending colon using Mouse Anti-Human Cadherin‑17 Monoclonal Antibody (Catalog # MAB1032) at 0.5 µg/mL overnight at 4 °C. ...read more
Cadherin‑17 was detected in immersion fixed paraffin-embedded sections of human transverse colon using Mouse Anti-Human Cadherin‑17 Monoclonal Antibody (Catalog # MAB1032) at 0.5 µg/mL overnight at 4 °C. ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clone
141713
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

View Available Formulations
Catalog# & Formulation Size Price
Carrier Free
MAB1032-SP
Carrier Free
MAB1032-500
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Cadherin-17 Antibody (141713) [Unconjugated] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human Cadherin‑17
Gln23-Met787
Accession # CAA58231
Specificity
Detects human Cadherin-17 in direct ELISAs and Western blots. In direct ELISAs and Western blots, this antibody does not cross-react with recombinant human (rh) Cadherin‑8, rhE‑Cadherin, rhP‑Cadherin, or rhVE‑Cadherin.
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
CDH17
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Immunohistochemistry 0.5-25 ug/mL
  • Western Blot 1 ug/mL
Publications
Read Publications using
MAB1032 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Cadherin-17 Antibody (141713) [Unconjugated]

  • cadherin 17, LI cadherin (liver-intestine)
  • cadherin
  • cadherin-16
  • Cadherin17
  • Cadherin-17
  • CDH16
  • CDH17
  • FLJ26931
  • HPT-1 cadherin
  • HPT1
  • HPT-1
  • human intestinal peptide-associated transporter HPT-1
  • human peptide transporter 1
  • Intestinal peptide-associated transporter HPT-1
  • LI cadherin
  • LI-cadherin
  • Liver-intestine cadherin
  • MGC138218
  • MGC142024

Background

Cadherin-17, also known as liver-intestine (LI) Cadherin, belongs to the cadherin family of calcium-dependent cell adhesion molecules. It associates homotypically and is selectively expressed on gastric and intestinal mucosa.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Cadherin-17 Antibody (MAB1032)(5)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 3 applications: ICC, IHC, Western Blot.


Filter By Application
ICC
(1)
IHC
(4)
Western Blot
(1)
All Applications
Filter By Species
Human
(4)
All Species
Showing Publications 1 - 5 of 5.
Publications using MAB1032 Applications Species
AK Eicher, DO Kechele, N Sundaram, HM Berns, HM Poling, LE Haines, JG Sanchez, K Kishimoto, M Krishnamur, L Han, AM Zorn, MA Helmrath, JM Wells Functional human gastrointestinal organoids can be engineered from three primary germ layers derived separately from pluripotent stem cells Cell Stem Cell, 2021-12-01;0(0):. 2021-12-01 [PMID: 34856121] (IHC, Human) IHC Human
T Wuensch, J Wizenty, J Quint, W Spitz, M Bosma, O Becker, A Adler, W Veltzke-Sc, M Stockmann, S Weiss, M Biebl, J Pratschke, F Aigner Expression Analysis of Fibronectin Type III Domain-Containing (FNDC) Genes in Inflammatory Bowel Disease and Colorectal Cancer Gastroenterol Res Pract, 2019-04-09;2019(0):3784172. 2019-04-09 [PMID: 31093274] (IHC, Human) IHC Human
Lin Z, Zhang C, Zhang M, Xu D, Fang Y, Zhou Z, Chen X, Qin N, Zhang X Targeting cadherin-17 inactivates Ras/Raf/MEK/ERK signaling and inhibits cell proliferation in gastric cancer. PLoS ONE, 2014-01-20;9(1):e85296. 2014-01-20 [PMID: 24465527] (IHC, Human) IHC Human
B. ALDHOON, T. KUČERA, N. SMORODINOVÁ, J. MARTÍNEK, V. MELENOVSKÝ, J. KAUTZNER Associations Between Cardiac Fibrosis and Permanent Atrial Fibrillation in Advanced Heart Failure Physiological Research 6/30/2013 [PMID: 23489193]
Luque-Garcia JL, Martinez-Torrecuadrada JL, Epifano C, Canamero M, Babel I, Casal JI Differential protein expression on the cell surface of colorectal cancer cells associated to tumor metastasis. Proteomics, 2010-03-01;10(5):940-52. 2010-03-01 [PMID: 20049862] (ICC, IHC, Western Blot, Human) ICC, IHC, Western Blot Human

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Bioinformatics

Gene Symbol CDH17
Uniprot