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BMP-1/PCP Antibody

Images

 
Immunohistochemistry-Paraffin: BMP-1/PCP Antibody [NBP1-87318] - Staining of human skeletal muscle shows low expression as expected.
Immunohistochemistry: BMP-1/PCP Antibody [NBP1-87318] - Staining of human duodenum shows cytoplasmic positivity in glandular cells.
Immunohistochemistry-Paraffin: BMP-1/PCP Antibody [NBP1-87318] - Staining of human placenta shows high expression.
Orthogonal Strategies: Immunohistochemistry-Paraffin: BMP-1/PCP Antibody [NBP1-87318] - Staining in human placenta and skeletal muscle tissues using anti-BMP1 antibody. Corresponding BMP1 RNA-seq data are ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
       

Orthogonal Strategies

 

Order Details

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BMP-1/PCP Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: DSEPLNYKDPCKAAAFLGDIALDEEDLRAFQVQQAVDLRRHTARKSSIKAAVPGNTSTPSCQSTNGQPQRGACGRWRGRSRSRRAATSRPERVWPDGVIPFVIGGNFTGS
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
BMP1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:20 - 1:50
  • Immunohistochemistry-Paraffin 1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
BMP-1/PCP Protein (NBP1-87318PEP)

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (80%)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for BMP-1/PCP Antibody

  • BMP1
  • BMP-1
  • bone morphogenetic protein 1
  • EC 3.4.24
  • EC 3.4.24.19
  • FLJ44432
  • Mammalian tolloid protein
  • mTld
  • PCOLC
  • PCP
  • PCP2
  • procollagen C-endopeptidase
  • Procollagen C-proteinase
  • TLD

Background

Bone morphogenetic protein 1 (BMP1) is a 986 amino acid member of the bone morphogenetic protein (BMP) family. It was initially discovered for its role to induce cartilage and bone formation. It is a metalloprotease that cleaves the C-terminus of procollagen I, II and III while other BMPs are part of the TGF beta superfamily. It may play a role in herniation, congestive heart failure, breast cancer, myelofibrosis with myeloid metaplasia and infection by HIV-1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol BMP1