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B7-H4 Antibody (973816) [PE/Cy7]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
973816
Clonality
Monoclonal
Host
Mouse
Conjugate
PE/Cy7

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB65761U-100UG
Alexa Fluor 405
FAB65761V-100UG
Alexa Fluor 488
FAB65761G-100UG
Alexa Fluor 532
FAB65761X
Alexa Fluor 594
FAB65761T-100UG
Alexa Fluor 647
FAB65761R-100UG
Alexa Fluor 700
FAB65761N-100UG
Alexa Fluor 750
FAB65761S-100UG
Allophycocyanin
FAB65761A
Allophycocyanin/Cy7
FAB65761APCCY7
Biotin
FAB65761B
CoraFluor 1
FAB65761CL1
DyLight 350
FAB65761D
DyLight 405
FAB65761E
DyLight 488
FAB65761K
DyLight 550
FAB65761L
DyLight 594
FAB65761M
DyLight 650
FAB65761W
DyLight 680
FAB65761Y
DyLight 755
FAB65761Z
FITC
FAB65761F
HRP
FAB65761H
Janelia Fluor 525
FAB65761JF525
Janelia Fluor 549
FAB65761I
Janelia Fluor 585
FAB65761JF585
Janelia Fluor 635
FAB65761JF635
Janelia Fluor 646
FAB65761J
Janelia Fluor 669
FAB65761JF669
PE
FAB65761P
PE/Atto594
FAB65761PEATT594
PE/Cy5.5
FAB65761PECY55
PerCP
FAB65761C
Unconjugated
MAB65761-100
mFluor Violet 450 SE
FAB65761MFV450
mFluor Violet 500 SE
FAB65761MFV500
mFluor Violet 610 SE
FAB65761MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB65761-100
Carrier Free
MAB65761-100
Carrier Free
MAB65761-SP
Carrier Free
FAB65761U-100UG
Carrier Free
FAB65761T-100UG
Carrier Free
FAB65761S-100UG
Carrier Free
FAB65761R-100UG
Carrier Free
FAB65761N-100UG
Carrier Free
FAB65761G-100UG
Carrier Free
FAB65761V-100UG
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B7-H4 Antibody (973816) [PE/Cy7] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human B7-H4
Phe29-Ala258
Accession # Q7Z7D3
Specificity
Detects human B7-H4 in direct ELISAs.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Purity
Protein A or G purified from hybridoma culture supernatant
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Applications/Dilutions

Dilutions
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined. For optimal results using our Tandem dyes, please avoid prolonged exposure to light or extreme temperature fluctuations. These can lead to irreversible degradation or decoupling. When staining intracellular targets, specific attention to the fixation and permeabilization steps in your flow protocol may be required. Please contact our technical support team at technical@novusbio.com if you have any questions.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Alternate Names for B7-H4 Antibody (973816) [PE/Cy7]

  • B7h.5
  • B7H4
  • B7-H4
  • B7H4T-cell costimulatory molecule B7x
  • B7S1
  • B7S1VCTN1
  • B7x
  • B7XPRO1291
  • FLJ22418
  • Immune costimulatory protein B7-H4
  • Protein B7S1
  • T cell costimulatory molecule B7x
  • V-set domain containing T cell activation inhibitor 1
  • V-set domain-containing T-cell activation inhibitor 1
  • Vtcn1

Background

B7H4 is a costimulatory protein which is reported to function as a negative regulator of T-cell mediated immunity. Although B7H4 binds an unknown receptor, it is thought to deliver an inhibitory signal to T-cells preventing their proliferation, cell cycle progression and interleukin-2 production. B7H4 deficient mice are only minimally affected, thus suggesting B7H4 is important in the fine tuning of the T-cell mediated immune response. B7H4 is expressed on activated T-cells, B-cells, monocytes and dendritic cells. Aberrant expression has been associated with cancers of the lung, breast and ovary in humans. B7H4 could be a useful prognostic marker in Renal Cell Carcinoma (RCC). There are three different isoforms.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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B7-H4 Antibody
(973816) [PE/Cy7]
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B7-H4 Antibody (973816) [PE/Cy7]
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