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Asialoglycoprotein Receptor 2 Antibody (OTI2A12) [PE]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clone
OTI2A12
Clonality
Monoclonal
Host
Mouse
Conjugate
PE

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-70212AF350
Alexa Fluor 405
NBP2-70212AF405
Alexa Fluor 488
NBP2-70212AF488
Alexa Fluor 532
NBP2-70212AF532
Alexa Fluor 594
NBP2-70212AF594
Alexa Fluor 647
NBP2-70212AF647
Alexa Fluor 700
NBP2-70212AF700
Alexa Fluor 750
NBP2-70212AF750
Allophycocyanin
NBP2-70212APC
Biotin
NBP2-70212B
CoraFluor 1
NBP2-70212CL1
DyLight 350
NBP2-70212UV
DyLight 405
NBP2-70212V
DyLight 488
NBP2-70212G
DyLight 550
NBP2-70212R
DyLight 594
NBP2-70212DL594
DyLight 650
NBP2-70212C
DyLight 680
NBP2-70212FR
DyLight 755
NBP2-70212IR
FITC
NBP2-70212F
HRP
NBP2-70212H
Janelia Fluor 525
NBP2-70212JF525
Janelia Fluor 549
NBP2-70212JF549
Janelia Fluor 646
NBP2-70212JF646
Janelia Fluor 669
NBP2-70212JF669
PerCP
NBP2-70212PCP
Unconjugated
NBP2-45505
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-45505
Azide and BSA Free
NBP2-70212
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Asialoglycoprotein Receptor 2 Antibody (OTI2A12) [PE] Summary

Immunogen
Full length human recombinant protein of human ASGR2 (NP_001172) produced in HEK293T cell.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
ASGR2
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Asialoglycoprotein Receptor 2 Antibody (OTI2A12) [PE]

  • ASGPR 2
  • ASGP-R 2
  • ASGPR2
  • ASGP-R2
  • ASGR2
  • asialoglycoprotein receptor 2
  • CLEC4H2
  • CLEC4H2FLJ60040
  • C-type lectin domain family 4 member H2
  • HBxAg-binding protein
  • HBXBP
  • Hepatic lectin H2
  • HL-2

Background

Asialoglycoprotein Receptor 2 is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of plasma glycoproteins in which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. It is expressed exclusively in hepatic parenchymal cells and calcium is required for ligand binding. Asialoglycoprotein Receptor 2 may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. Asialoglycoprotein Receptor 2 is involved in hepatitis B, hepatitis C, liver cirrhosis, hepatocellular carcinoma, nephropathy, leukemia, urethritis, autoimmune hepatitis, alcoholic liver cirrhosis, and jaundice.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol ASGR2