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Asialoglycoprotein Receptor 2 Antibody (OTI2A12)

Images

 
Western Blot: Asialoglycoprotein Receptor 2 Antibody (OTI2A12) [NBP2-45505] - Human ASGR2 over-expressing cells. Western blot image submitted by a verified customer review.
Immunohistochemistry: Asialoglycoprotein Receptor 2 Antibody (OTI2A12) [NBP2-45505] - Analysis of Carcinoma of Human liver tissue. Heat-induced epitope retrieval by 10 mM citric buffer, pH 6.0, 120C for 3 minutes.
Western Blot: Asialoglycoprotein Receptor 2 Antibody (OTI2A12) [NBP2-45505] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY Asialoglycoprotein receptor 2.
Immunohistochemistry: Asialoglycoprotein Receptor 2 Antibody (OTI2A12) [NBP2-45505] - Analysis of Adenocarcinoma of Human colon tissue. Heat-induced epitope retrieval by 10 mM citric buffer, pH 6.0, 120C for 3 minutes.
Immunohistochemistry: Asialoglycoprotein Receptor 2 Antibody (OTI2A12) [NBP2-45505] - Analysis of Adenocarcinoma of Human endometrium tissue. Heat-induced epitope retrieval by 10 mM citric buffer, pH 6.0, 120C for 3 ...read more
Immunohistochemistry: Asialoglycoprotein Receptor 2 Antibody (OTI2A12) [NBP2-45505] - Analysis of Human lymph node tissue. Heat-induced epitope retrieval by 10 mM citric buffer, pH 6.0, 120C for 3 minutes.
Immunohistochemistry: Asialoglycoprotein Receptor 2 Antibody (OTI2A12) [NBP2-45505] - Analysis of Carcinoma of Human thyroid tissue. Heat-induced epitope retrieval by 10 mM citric buffer, pH 6.0, 120C for 3 minutes.
Immunohistochemistry: Asialoglycoprotein Receptor 2 Antibody (OTI2A12) [NBP2-45505] - Analysis of Adenocarcinoma of Human ovary tissue. Heat-induced epitope retrieval by 10 mM citric buffer, pH 6.0, 120C for 3 minutes.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clone
OTI2A12
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

Asialoglycoprotein Receptor 2 Antibody (OTI2A12) Summary

Immunogen
Full length human recombinant protein of human ASGR2 (NP_001172) produced in HEK293T cell.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
ASGR2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:150
  • Immunohistochemistry-Paraffin
  • Western Blot 1:4000
Theoretical MW
35 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Reviewed Applications
Read 1 Review rated 5
using
NBP2-45505 in the following applications:

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.3), 1% BSA, 50% Glycerol
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Asialoglycoprotein Receptor 2 Antibody (OTI2A12)

  • ASGPR 2
  • ASGP-R 2
  • ASGPR2
  • ASGP-R2
  • ASGR2
  • asialoglycoprotein receptor 2
  • CLEC4H2
  • CLEC4H2FLJ60040
  • C-type lectin domain family 4 member H2
  • HBxAg-binding protein
  • HBXBP
  • Hepatic lectin H2
  • HL-2

Background

Asialoglycoprotein Receptor 2 is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of plasma glycoproteins in which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. It is expressed exclusively in hepatic parenchymal cells and calcium is required for ligand binding. Asialoglycoprotein Receptor 2 may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. Asialoglycoprotein Receptor 2 is involved in hepatitis B, hepatitis C, liver cirrhosis, hepatocellular carcinoma, nephropathy, leukemia, urethritis, autoimmune hepatitis, alcoholic liver cirrhosis, and jaundice.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Review for Asialoglycoprotein Receptor 2 Antibody (NBP2-45505) (1) 51

Average Rating: 5
(Based on 1 review)
We have 1 review tested in 1 species: Human.

Reviews using NBP2-45505:
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WB
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Images Ratings Applications Species Date Details
Western Blot Asialoglycoprotein Receptor 2 NBP2-45505
Enlarge
5
reviewed by:
Verified Customer
WB Human 10/11/2019
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Summary

ApplicationWestern Blot
Sample TestedASGR2 over-expressing cells
SpeciesHuman
LotW001

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Recent Reviews

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Verified Customer
10/11/2019
Application: WB
Species: Human

Bioinformatics

Gene Symbol ASGR2