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Arylsulfatase B/ARSB Antibody

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Orthogonal Strategies: Immunohistochemistry-Paraffin: Arylsulfatase B/ARSB Antibody [NBP1-85879] - Staining in human kidney and liver tissues using anti-ARSB antibody. Corresponding ARSB RNA-seq data are ...read more
Immunohistochemistry-Paraffin: Arylsulfatase B/ARSB Antibody [NBP1-85879] - Staining of human liver shows low expression as expected.
Immunohistochemistry-Paraffin: Arylsulfatase B/ARSB Antibody [NBP1-85879] - Staining of human kidney shows high expression.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
       

Orthogonal Strategies

 

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Arylsulfatase B/ARSB Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: TRCALDFRDGEEVATGYKNMYSTNIFTKRAIALITNHPPEKPLFLYLALQSVHEPLQVPEEYLKPYDFIQDKNRHHYAGMVSLMDEAVGNVT
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ARSB
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
Arylsulfatase B/ARSB Protein (NBP1-85879PEP)

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (80%), Rat (80%)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Arylsulfatase B/ARSB Antibody

  • ARSB
  • Arylsulfatase B
  • ASB
  • EC 3.1.6.12
  • G4S
  • MPS6
  • N-acetylgalactosamine-4-sulfatase

Background

Arylsulfatase B encoded by this gene belongs to the sulfatase family. The arylsulfatase B homodimer hydrolyzes sulfate groups of N-Acetyl-D-galactosamine, chondriotin sulfate, and dermatan sulfate. The protein is targetted to the lysozyme. Mucopolysaccharidosis type VI is an autosomal recessive lysosomal storage disorder resulting from a deficiency of arylsulfatase B. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol ARSB
Entrez
Uniprot