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APBA3/Mint-3 Antibody [Unconjugated]

Name: APBA3/Mint-3 Antibody [Unconjugated]
Brand: Novus Biologicals
SKU: AF5689
Price: 459 USD

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Western blot shows lysates of HeLa human cervical epithelial carcinoma cell line. PVDF membrane was probed with 1 µg/mL of Sheep Anti-Human APBA3 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF5689) ...read more

Product Details

Summary

Reactivity	HuSpecies Glossary
Applications	WB
Clonality	Polyclonal
Host	Sheep
Conjugate	Unconjugated
Concentration	LYOPH

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Catalog# & Formulation	Size	Price
Carrier Free AF5689-SP

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APBA3/Mint-3 Antibody [Unconjugated] Summary

Immunogen	E. coli-derived recombinant human APBA3 Met1-Leu138 Accession # O96018
Specificity	Detects human APBA3 in direct ELISAs and Western blots. In direct ELISAs, less than 1% cross‑reactivity with recombinant human (rh) X11‑ alpha and rhX11-beta is observed.
Source	N/A
Isotype	IgG
Clonality	Polyclonal
Host	Sheep
Gene	APBA3
Purity Statement	Antigen Affinity-purified
Innovator's Reward	Test in a species/application not listed above to receive a full credit towards a future purchase. Learn about the Innovator's Reward

Applications/Dilutions

Dilutions

Western Blot 1 ug/mL

Packaging, Storage & Formulations

Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer	Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative	No Preservative
Concentration	LYOPH
Reconstitution Instructions	Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for APBA3/Mint-3 Antibody [Unconjugated]

Adapter protein X11gamma
amyloid beta (A4) precursor protein-binding, family A, member 3 (X11-like 2)
amyloid beta (A4) precursor protein-binding, family A, member 3
APBA3
MGC:15815
MINT3
mint-3
Neuronal Munc18-1-interacting protein 3
Neuron-specific X11L2 protein
phosphotyrosine-binding/-interacting domain (PTB)-bearing protein
X11L2
X11L2amyloid beta A4 precursor protein-binding family A member 3
X11-like 2 protein

Background

X11-gamma (Adaptor protein X11 gamma; also APBA3, Mint3 and X11L2) is a member of the X11 family of adaptor proteins. Unlike X11 alpha and -beta which are generally neuronal proteins, X11-gamma is widely expressed in all tissues. X11-gamma has many functions, including MT-MMP and Furin intracellular trafficking and APP binding. Human X11-gamma is 575 amino acids (aa) in length. It contains a poly-Ser segment (aa 165‑171), a PID region (aa 217‑381) that binds beta -amyloid precursor, and two PDZ domains (aa 393‑478 and 485‑560) that bind Arf GTPases. There is one potential splice variant that shows a 34 aa insertion after Ile505. Over aa 1‑138, human X11‑ gamma shares 62% aa identity with mouse X11‑ gamma .

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol	APBA3
Uniprot	O96018(Human)

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At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

APBA3/Mint-3 Antibody [Unconjugated]

Species Glossary

Images

Product Details

Order Details

APBA3/Mint-3 Antibody [Unconjugated] Summary

Applications/Dilutions

Packaging, Storage & Formulations

Notes

Alternate Names for APBA3/Mint-3 Antibody [Unconjugated]

Background

Limitations

Customers Who Viewed This Item Also Viewed...

Publications for APBA3/Mint-3 Antibody (AF5689) (0)

Reviews for APBA3/Mint-3 Antibody (AF5689) (0)

Product General Protocols

Video Protocols

FAQs for APBA3/Mint-3 Antibody (AF5689) (0)

Secondary Antibodies

Isotype Controls

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Bioinformatics