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Aminopeptidase A/ENPEP Antibody

Images

 
Immunohistochemistry-Paraffin: Aminopeptidase A/ENPEP Antibody [NBP1-85774] - Staining of human stomach shows low expression as expected.
Immunohistochemistry-Paraffin: Aminopeptidase A/ENPEP Antibody [NBP1-85774] - Staining of human small intestine shows high expression.
Orthogonal Strategies: Immunohistochemistry-Paraffin: Aminopeptidase A/ENPEP Antibody [NBP1-85774] - Staining in human small intestine and stomach tissues using anti-ENPEP antibody. Corresponding ENPEP RNA-seq ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
       

Orthogonal Strategies

 

Order Details

Aminopeptidase A/ENPEP Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: SHLPSSTASPSGPPAQDQDICPASEDESGQWKNFRLPDFVNPVHYDLHVKPLLEEDTYTGTVSISINLSAPTRYLWLHLRETRITRLPELKRPSGDQVQVRRCFEYKKQEYVVVE
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ENPEP
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:500 - 1:1000
  • Immunohistochemistry-Paraffin 1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
Aminopeptidase A/ENPEP Protein (NBP1-85774PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Aminopeptidase A/ENPEP Antibody

  • Aminopeptidase A
  • APA
  • AP-A
  • CD249 antigen
  • CD249
  • Differentiation antigen gp160
  • EAP
  • EC 3.4.11
  • EC 3.4.11.7
  • ENPEP
  • glutamyl aminopeptidase (aminopeptidase A)
  • glutamyl aminopeptidase
  • gp160

Background

Aminopeptidase A is a zinc-dependent metallopeptidase that selectively cleaves N-terminal Glu, or Asp residues from peptides. In mice, it is expressed on early B cells and on a subset of thymic cortical epithelial cells, but not on mature lymphocytes. Additionally, it is expressed on endothelial cells, intestinal epithelium, proximal renal tubules, and other non-hemopoietic tissues. In humans, angiotensin II is the the best-defined biologically active substrate of APA. Although its role in the immune response is still uncertain, its expression on renal cell carcinoma has been the focus of some cancer research studies.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol ENPEP