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AlphaB Crystallin/CRYAB Antibody [DyLight 550]

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Product Details

Summary
Reactivity Hu, Mu, Rt, Po, Ch, Gp, Pm, Rb, ShSpecies Glossary
Applications WB, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 550

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB100-2519AF350
Alexa Fluor 405
NB100-2519AF405
Alexa Fluor 488
NB100-2519AF488
Alexa Fluor 532
NB100-2519AF532
Alexa Fluor 594
NB100-2519AF594
Alexa Fluor 647
NB100-2519AF647
Alexa Fluor 700
NB100-2519AF700
Alexa Fluor 750
NB100-2519AF750
Allophycocyanin
NB100-2519APC
Biotin
NB100-2519B
CoraFluor 1
NB100-2519CL1
DyLight 350
NB100-2519UV
DyLight 405
NB100-2519V
DyLight 488
NB100-2519G
DyLight 594
NB100-2519DL594
DyLight 650
NB100-2519C
DyLight 680
NB100-2519FR
DyLight 755
NB100-2519IR
FITC
NB100-2519F
HRP
NB100-2519H
Janelia Fluor 525
NB100-2519JF525
Janelia Fluor 549
NB100-2519JF549
Janelia Fluor 585
NB100-2519JF585
Janelia Fluor 635
NB100-2519JF635
Janelia Fluor 646
NB100-2519JF646
Janelia Fluor 669
NB100-2519JF669
PE
NB100-2519PE
PerCP
NB100-2519PCP
Unconjugated
NB100-2519
mFluor Violet 450 SE
NB100-2519MFV450
mFluor Violet 500 SE
NB100-2519MFV500
mFluor Violet 610 SE
NB100-2519MFV610
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AlphaB Crystallin/CRYAB Antibody [DyLight 550] Summary

Immunogen
A synthetic peptide made to an internal region of the human Crystallin AB protein (within residues 70-140). [Swiss-Prot P02511]
Localization
Cytoplasmic
Predicted Species
Rat (100%), Porcine (100%), Guinea Pig (100%), Rabbit (100%), Chicken (100%), Sheep (100%), Primate (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CRYAB
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Predicted to react with rat, sheep, rabbit, monkey, guinea pig, chicken, and pig based on 100% sequence homology. Immunogen sequence has 81% homology with Zebrafish.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for AlphaB Crystallin/CRYAB Antibody [DyLight 550]

  • alpha B crystallin
  • alpha(B)-crystallin
  • AlphaB Crystallin
  • alpha-crystallin B chain
  • CRYA2
  • CRYA2alpha crystallin B chain
  • CRYAB
  • crystallin, alpha B
  • CTPP2
  • Heat shock protein beta-5
  • heat-shock 20 kD like-protein
  • HSPB5
  • Renal carcinoma antigen NY-REN-27
  • Rosenthal fiber component

Background

Crystallin AB (CryAB) is a developmentally regulated small heat shock protein known to protect cells from stress damage. It may also play an important role in the Golgi reorganization during cell division. CryAB is known to be associated with a number of neurodegenerative pathologies such as Alzheimer disease amd multiple sclerosis. As well, it has been found to be expressed in breast tumors of patients with shorter survival, suggesting that it may be a useful marker in identifying aggressive breast cancer.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol CRYAB