ALDH2 Antibody (1E5)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of the mitochondrial isozyme. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Showing Publications 1 - 4 of 4.

Publications using H00000217-M01	Applications	Species
Ichikawa H, Kanda T, Kosugi SI et al. Laser Microdissection and Two-Dimensional Difference Gel Electrophoresis Reveal the Role of a Novel Macrophage-Capping Protein in Lymph Node Metastasis in Gastric Cancer. J Proteome Res. 2013-07-09 [PMID: 23782053]
Jeon J, Jeong JH, Baek JH et al. Network Clustering Revealed the Systemic Alterations of Mitochondrial Protein Expression. PLoS Comput Biol 2011-06-30 [PMID: 21738461]
Kitamura H, Ito M, Yuasa T et al. Genome-wide identification and characterization of transcripts translationally regulated by bacterial lipopolysaccharide in macrophage-like J774.1 cells. Physiol Genomics 2008-01-29 [PMID: 18230670]
Xu L, Han S, Chen Z et al. Increase of Oxidative Stress by Deficiency of The ALDH2/UCP2/Nrf2 Axis Exacerbates Cardiac Dysfunction in Chronic Kidney Disease Reviews in Cardiovascular Medicine 2022-04-02

Array H00000217-M01

• ALDH2 Antibodies
• ALDH2 ELISA Kits
• ALDH2 Lysate
• ALDH2 Proteins