ALDH18A1 Antibody (2B5)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This gene is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities. The encoded protein catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate, a critical step in the de novo biosynthesis of proline, ornithine and arginine. Mutations in this gene lead to hyperammonemia, hypoornithinemia, hypocitrullinemia, hypoargininemia and hypoprolinemia and may be associated with neurodegeneration, cataracts and connective tissue diseases. Alternatively spliced transcript variants, encoding different isoforms, have been described for this gene.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

Showing Publication 1 - 1 of 1.

Publication using H00005832-M01	Applications	Species
De Ingeniis J, Ratnikov B, Richardson AD et al. Functional specialization in proline biosynthesis of melanoma. PLoS One. 2012-01-01 [PMID: 23024808] (Human)		Human

Array H00005832-M01

• ALDH18A1 Antibodies
• ALDH18A1 Lysate
• ALDH18A1 Proteins