ADAM19 Antibody

ADAM19 is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a type I transmembrane protein and serves as a marker for dendritic cell differentiation. It has also been demonstrated to be an active metalloproteinase, which may be involved in normal physiological and pathological processes such as cells migration, cell adhesion, cell-cell and cell-matrix interactions, and signal transduction. Alternative splicing results in two transcript variants.This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a type I transmembrane protein and serves as a marker for dendritic cell differentiation. It has also been demonstrated to be an active metalloproteinase, which may be involved in normal physiological and pathological processes such as cells migration, cell adhesion, cell-cell and cell-matrix interactions, and signal transduction. Alternative splicing results in two transcript variants.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 3 applications: ICC/IF, IF/IHC, WB.

Showing Publications 1 - 5 of 5.

Publications using NBP1-69364	Applications	Species
Klapproth E, Witt A, Klose P et al. Targeting cardiomyocyte ADAM10 ectodomain shedding promotes survival early after myocardial infarction Nature communications 2022-12-10 [PMID: 36496449] (WB, Mouse) Details: Dilution used in WB 1:1000	WB	Mouse
Ryu J, Choe N, Kwon D et al. Circular RNA circSmoc1-2 regulates vascular calcification by acting as a miR-874-3p sponge in vascular smooth muscle cells Molecular Therapy - Nucleic Acids 2022-03-01 [PMID: 35036071] (IF/IHC, WB)	IF/IHC, WB
Kanda A, Noda K, Saito W, Ishida S. (Pro)renin receptor is associated with angiogenic activity in proliferative diabetic retinopathy Diabetologia 2012-08-30 [PMID: 22930161] (IF/IHC, ICC/IF, Mouse)	IF/IHC, ICC/IF	Mouse
Tanabe,C. Biochem. Biophys. Res. Commun. 352 (1), 111-117. 2007-01-01 [PMID: 17112471]
Glesne DA, Zhang W, Mandava S et al. Subtractive transcriptomics: establishing polarity drives in vitro human endothelial morphogenesis. Cancer Res. 2006-04-01 [PMID: 16618722] (ICC/IF, Human)	ICC/IF	Human

Images	Ratings	Applications	Species	Date	Details
Enlarge	5 reviewed by: Verified Customer	WB	Human	10/06/2014	View Summary Application Western Blot Sample Tested Whole cell lysate from HeLa cells Species Human

Array NBP1-69364

• ADAM19 Antibodies
• ADAM19 ELISA Kits
• ADAM19 Lysate