ADAM12 Antibody

This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene has two alternatively spliced transcripts: a shorter secreted form and a longer membrane-bound form. The shorter form is found to stimulate myogenesis.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 1 application: IF/IHC.

Showing Publications 1 - 4 of 4.

Publications using NB300-889	Applications	Species
Chen, J;Sobecki, M;Krzywinska, E;Thierry, K;Masmoudi, M;Nagarajan, S;Fan, Z;He, J;Ferapontova, I;Nelius, E;Seehusen, F;Gotthardt, D;Takeda, N;Sommer, L;Sexl, V;Münz, C;DeNardo, D;Hennino, A;Stockmann, C; Fibrolytic vaccination against ADAM12 reduces desmoplasia in preclinical pancreatic adenocarcinomas EMBO molecular medicine 2024-10-30 [PMID: 39478152]
M Sobecki, J Chen, E Krzywinska, S Nagarajan, Z Fan, E Nelius, JM Monné Rodr, F Seehusen, A Hussein, G Moschini, EY Hajam, R Kiran, D Gotthardt, J Debbache, C Badoual, T Sato, T Isagawa, N Takeda, C Tanchot, E Tartour, A Weber, S Werner, J Loffing, L Sommer, V Sexl, C Münz, C Feghali-Bo, E Pachera, O Distler, J Snedeker, C Jamora, C Stockmann Vaccination-based immunotherapy to target profibrotic cells in liver and lung Cell Stem Cell, 2022-09-15;0(0):. 2022-09-15 [PMID: 36113462]
Isozaki T, Rabquer BJ, Ruth JH et al. ADAM-10 is overexpressed in rheumatoid arthritis synovial tissue and mediates angiogenesis Arthritis Rheum 2013-01-01 [PMID: 23124962] (IF/IHC, Mouse, Human)	IF/IHC	Mouse, Human
Galliano MF, Huet C, Frygelius J et al. Binding of ADAM12, a marker of skeletal muscle regeneration, to themuscle-specific actin-binding protein, alpha -actinin-2, is required formyoblast fusion. J Biol Chem 2000-05-05 [PMID: 10788519]

Array NB300-889

• ADAM12 Antibodies
• ADAM12 Lysate
• ADAM12 Proteins
• ADAM12 Proteins and Enzyme
• ADAM12 ELISAs