ACE/CD143 Activity Assay Kit (Colorimetric) Summary
Description |
Detection instrument: Spectrophotometer (340nm) Assay time: 10 - 90 min |
Standard Curve Range |
27.5 - 682 U/L |
Sensitivity |
27.5 U/L |
Inter-Assay |
%CV < 4.4 |
Intra-Assay |
%CV < 3 |
Spike Recovery |
Average recovery rate: 103% |
Kit Type |
Activity Assay Kit (Colorimetric) |
Gene |
ACE |
Applications/Dilutions
Packaging, Storage & Formulations
Storage |
Storage of components varies. See protocol for specific instructions. |
Kit Components
Components
|
- Reagent 1: Working Solution
|
Alternate Names for ACE/CD143 Activity Assay Kit (Colorimetric)
Background
ACE converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilatator. ACE exists in two forms, a 170KD somatic form and a 90KD germinal form. The somatic form is expressed by endothelial cells (especially those of lung capillaries and arterioles), epithelial cells (especially in proximal renal tubules and small intestine), by some neuronal cells and variably by some macrophages and T lymphocytes. The germinal form is expressed by spermatozoa.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Kits are
guaranteed for 6 months from date of receipt.
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