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ABCB11 Antibody - Azide and BSA Free

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Immunocytochemistry/ Immunofluorescence: ABCB11 Antibody [NBP2-92689] - Immunofluorescence analysis of HeLa cells using ABCB11 antibody (NBP2-92689) at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunocytochemistry/ Immunofluorescence: ABCB11 Antibody [NBP2-92689] - Analysis of NIH-3T3 cells using ABCB11 . Blue: DAPI for nuclear staining.
Western Blot: ABCB11 Antibody - Azide and BSA Free [NBP2-92689] - Western blot analysis of lysates from Mouse liver, using ABCB11 Rabbit pAb at 1:1000 dilution.Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG ...read more

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
Azide and BSA Free

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ABCB11 Antibody - Azide and BSA Free Summary

Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1050-1150 of human ABCB11 (NP_003733.2). RFFQLLDRQPPISVYNTAGEKWDNFQGKIDFVDCKFTYPSRPDSQVLNGLSVSISPGQTLAFVGSSGCGKSTSIQLLERFYDPDQGKVMIDGHDSKKVNVQ
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ABCB11
Purity
Affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 1:50 - 1:200
  • Western Blot 1:500 - 1:1000
Theoretical MW
146 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.3), 50% glycerol
Preservative
0.09% Sodium Azide
Purity
Affinity purified

Alternate Names for ABCB11 Antibody - Azide and BSA Free

  • ABC member 16, MDR/TAP subfamily
  • ABC16
  • ATP-binding cassette sub-family B member 11
  • ATP-binding cassette, sub-family B (MDR/TAP), member 11
  • bile salt export pump
  • BSEP
  • BSEPPFIC2
  • EC 3.6.3
  • EC 3.6.3.44
  • PFIC-2
  • PGY4
  • progressive familial intrahepatic cholestasis 2
  • sister p-glycoprotein
  • SPGPBRIC2

Background

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including Methotrexate, which is known to the State of California to cause reproductive toxicity with developmental effects. For more information, go to www.P65Warnings.ca.gov

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol ABCB11