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A2BP1 Antibody (1G10)

Images

 
Western Blot: A2BP1 Antibody (1G10) [NBP3-11943] - Western blot of rat cortical lysate showing specific immunolabeling of the ~46/48 kDa A2BP1 protein.
Immunocytochemistry/ Immunofluorescence: A2BP1 Antibody (1G10) [NBP3-11943] - Immunofluorescence of cultured rat neurons showing nuclear and distal cytoplasmic labeling of A2BP1 (cat. NBP3-11943, 1:500, green).

Product Details

Summary
Reactivity Hu, Mu, Rt, BvSpecies Glossary
Applications WB, ICC/IF, IHC
Clone
1G10
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

A2BP1 Antibody (1G10) Summary

Description
Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage).
Immunogen
Recombinant protein taken from the N-terminus of A2BP1 expressed in and purified from E. Coli. (UniProt: Q9NWB1)
Specificity
Specific for endogenous levels of the ~46/48 kD FOX1 protein doublet.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
RBFOX1
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 1:500
  • Immunohistochemistry 1:500
  • Western Blot 1:5000
Theoretical MW
46 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C.
Buffer
100 ul in PBS
Preservative
0.07% Sodium Azide
Purity
Protein G purified

Alternate Names for A2BP1 Antibody (1G10)

  • 2BP1
  • A2BP
  • A2BP1 Hexaribonucleotide-binding protein 1
  • Ataxin-2-binding protein 1
  • FOX1 hexaribonucleotide binding protein 1
  • Fox-1 homolog A
  • FOX-1
  • HRNBP1 ataxin 2-binding protein 1
  • RNA binding protein fox-1 homolog 1
  • RNA binding protein, fox-1 homolog (C. elegans) 1

Background

Ataxin-2 binding protein 1 has an RNP motif that is highly conserved among RNA-binding proteins. This protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the gene product of the SCA2 gene which causes familial neurodegenerative diseases. Ataxin-2 binding protein 1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been found but their full length nature has not been determined. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol RBFOX1