Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Mouse Monoclonal
Species: Hu, Mu
Applications: WB, Func, ICC/IF
Host: Rabbit Polyclonal
Species: Hu, Mu
Applications: WB, ICC/IF
Host: Mouse Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: WB, ELISA, MA, PAGE, AP
Species: Hu
Applications: AC
Description
ERCC8 encodes a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcription factor IIH. Mutations in this gene have been identified in patients with hereditary disease Cockayne syndrome (CS). CS cells are abnormally sensitive to ultraviolet radiation and are defective in the repair of transcriptionally active genes.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
Human
Human
Human
|
| Product By Gene ID |
1161 |
| Alternate Names |
- CKN1DNA excision repair protein ERCC-8
- Cockayne syndrome 1 (classical)
- Cockayne syndrome WD repeat protein CSA
- CSACockayne syndrome WD-repeat protein CSA
- excision repair cross-complementing rodent repair deficiency, complementationgroup 8
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Related ERCC8 Blog Posts
Check out the latest blog posts on ERCC8.
NER Antibodies in Cancer Research
We at Novus Biologicals have over 230 products in our antibody catalog devoted to nucleotide excision repair. NER is a multi-stage sequential process involving over 30 proteins, all of which have been widely studied. Being the primary method to repair... Read more.
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Read more ERCC8 related blogs.
