Dkk-1 Products

Description

DKK1 is a secreted factor that has been linked to the function of osteoblasts. Elevated DKK1 levels in bone marrow plasma and peripheral blood from patients with multiple myeloma correlated with the gene-expression patterns of DKK1 and were associated with the presence of focal bone lesions. The production of DKK1, an inhibitor of osteoblast differentiation, by myeloma cells is associated with the presence of lytic bone lesions in patients with multiple myeloma.

Bioinformatics

Entrez	13380 Mouse 22943 Human
Uniprot	AAH01539 Human AAH01539.1 Human NM_012242 Human NP_036374 Human NP_036374. Human NP_036374.1 Human O54908 Mouse O94907 Human
Product By Gene ID	22943
Alternate Names	dickkopf (Xenopus laevis) homolog 1 dickkopf homolog 1 (Xenopus laevis) dickkopf related protein-1 Dickkopf-1 dickkopf-related protein 1 DKK-1 Dkk-1 hDkk-1 SKdickkopf-1 like

Research Areas for Dkk-1

Find related products by research area and learn more about each of the different research areas below.

Immunology
Innate Immunity
Signal Transduction
Stem Cell Signaling Pathway
Wnt Signaling Pathway

Related Dkk-1 Blog Posts

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The role of Wnts in neuroinflammation By Michalina Hanzel, PhDThe multifaceted roles of the Wnt family of glycoproteins have been extensively characterized throughout embryonic development and adult homeostasis. The highly conserved, cell- and tissue- s...    Read more.

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