Septin-4 Products

Description

Apoptosis is related to many diseases and development. Mitochondrial proteins, such as cytochrome c, Apaf-1, and AIF play important role in apoptosis. A novel mitochondrial septin-like protein was identified recently and designated ARTS for apoptosis related protein in TGF-b signaling pathway. ARTS that is encoded by the human septin H5/PNUTL2/CDCrel2b gene is located to mitochondria and translocates to the nucleus when apoptosis occurs. ARTS is expressed in many tissues. It enhances cell death induced by TGF-b and, to a lesser extent, by other apoptotic agents, such as TNF-a and Fas ligand.

Bioinformatics

Entrez	18952 Mouse 5414 Human
Uniprot	AAG45673 Human NP_004565 Human NP_004565.1 Human O43236 Human
Product By Gene ID	5414
Alternate Names	Apoptosis-related protein in the TGF-beta signaling pathway ARTSPeanut-like protein 2 Bradeion beta BRADEION Brain protein H5 CE5B3 Cell division control-related protein 2 Cerebral protein 7 H5 hCDCREL-2SEP4 hucep-7 MART peanut-like 2 (Drosophila) peanut-like 2 PNUTL2CE5B3 beta septin 4 septin-4 septin-M

Research Areas for Septin-4

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Apoptosis