Home » VEGFR1/Flt-1 » VEGFR1/Flt-1 Antibodies » VEGFR1/Flt-1 Antibody (49560) [Allophycocyanin]
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VEGFR1/Flt-1 Antibody (49560) [Allophycocyanin]

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HUVEC human umbilical vein endothelial cells were stained with Mouse Anti-Human VEGF R1/Flt-1 APC-conjugated Monoclonal Antibody (Catalog # FAB321A, filled histogram) or isotype control antibody (Catalog # IC002A, open histogram). View our protocol for Staining Membrane-associated Proteins.
HUVEC human umbilical vein endothelial cells were stained with Mouse Anti-Human VEGF R1/Flt-1 APC-conjugated Monoclonal Antibody (Catalog # FAB321A, filled histogram) or isotype control antibody (Catalog # IC002A, open ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
49560
Clonality
Monoclonal
Host
Mouse
Conjugate
Allophycocyanin

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB321U-100UG
Alexa Fluor 405
FAB321V-100UG
Alexa Fluor 488
FAB321G-100UG
Alexa Fluor 532
FAB321X
Alexa Fluor 594
FAB321T-100UG
Alexa Fluor 647
FAB321R-100UG
Alexa Fluor 700
FAB321N-100UG
Alexa Fluor 750
FAB321S-100UG
Allophycocyanin/Cy7
FAB321APCCY7
Biotin
FAB321B
CoraFluor 1
FAB321CL1
DyLight 350
FAB321D
DyLight 405
FAB321E
DyLight 488
FAB321K
DyLight 550
FAB321L
DyLight 594
FAB321M
DyLight 650
FAB321W
DyLight 680
FAB321Y
DyLight 755
FAB321Z
FITC
FAB321F
HRP
FAB321H
Janelia Fluor 525
FAB321JF525
Janelia Fluor 549
FAB321I
Janelia Fluor 646
FAB321J
Janelia Fluor 669
FAB321JF669
PE/Atto594
FAB321PEATT594
PE/Cy5.5
FAB321PECY55
PE/Cy7
FAB321PECY7
PerCP
FAB321C
Phycoerythrin
FAB321P
Unconjugated
MAB321-100
mFluor Violet 450 SE
FAB321MFV450
mFluor Violet 500 SE
FAB321MFV500
mFluor Violet 610 SE
FAB321MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB321-100
Carrier Free
FAB321P
Carrier Free
MAB321-100
Carrier Free
MAB321-SP
Carrier Free
FAB321V-100UG
Carrier Free
FAB321U-100UG
Carrier Free
FAB321T-100UG
Carrier Free
FAB321S-100UG
Carrier Free
FAB321R-100UG
Carrier Free
FAB321N-100UG
Carrier Free
FAB321G-100UG
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VEGFR1/Flt-1 Antibody (49560) [Allophycocyanin] Summary

Immunogen
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human VEGF R1/Flt-1
Ser27-His687
Accession # NP_001153392
Specificity
Detects human VEGF R1/Flt-1 in direct ELISAs and Western blots. In Western blots, this antibody does not cross-react with recombinant mouse VEGF R1, recombinant human (rh) VEGF R2, rhVEGF R3, or rhVEGF R4.
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
FLT1
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Flow Cytometry 10 uL/10^6 cells
Publications
Read Publications using
FAB321A in the following applications:

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for VEGFR1/Flt-1 Antibody (49560) [Allophycocyanin]

  • EC 2.7.10
  • EC 2.7.10.1
  • FLT
  • FLT1
  • Flt-1
  • Fms-like tyrosine kinase 1
  • fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascularpermeability factor receptor)
  • FRT
  • Tyrosine-protein kinase FRT
  • Tyrosine-protein kinase receptor FLT
  • vascular endothelial growth factor receptor 1
  • Vascular permeability factor receptor
  • VEGF R1
  • VEGFR1
  • VEGFR-1

Background

Vascular Endothelial Growth Factor Receptor 1 (VEGF R1) is a receptor tyrosine kinase that is expressed primarily on endothelial cells and plays a role in vasculogenesis and angiogenesis. A soluble variant of VEGF R1 was also reported to bind VEGF and PlGF with high affinity and function as a potent VEGF antagonist.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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VEGF-C [HRP]
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N/A Angiopoietin-2 [HRP]
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Publications for VEGFR1/Flt-1 Antibody (FAB321A)(7)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: Flow Cytometry.


Filter By Application
Flow Cytometry
(7)
All Applications
Filter By Species
Human
(7)
All Species
Showing Publications 1 - 7 of 7.
Publications using FAB321A Applications Species
S Schwinn, Z Mokhtari, S Thusek, T Schneider, AL Sirén, N Tiemeyer, I Caruana, E Miele, PG Schlegel, A Beilhack, M Wölfl Cytotoxic effects and tolerability of gemcitabine and axitinib in a xenograft model for c-myc amplified medulloblastoma Scientific Reports, 2021-07-07;11(1):14062. 2021-07-07 [PMID: 34234256] (Flow Cytometry, Human) Flow Cytometry Human
Fiorio Pla , Alessand, Brossa , Alessia, Bernardini , Michela, Genova , Tullio, Grolez , Guillaum, Villers , Arnaud, Leroy , Xavier, Prevarskaya , Natalia, Gkika , Dimitra, Bussolati , Benedett Differential sensitivity of prostate tumor derived endothelial cells to sorafenib and sunitinib. BMC Cancer, 2014-12-12;14(0):939. 2014-12-12 [PMID: 25494980] (Flow Cytometry, Human) Flow Cytometry Human
Lohri C, Schaltegger C, van den Broek M, Wenger R, Ruegg C, Fink D, Fehr M, Knuth A, Zweifel M Neutrophil expression of ICAM1, CXCR1, and VEGFR1 in patients with breast cancer before and after adjuvant chemotherapy. Anticancer Res, 2014-09-01;34(9):4693-9. 2014-09-01 [PMID: 25202046] (Flow Cytometry, Human) Flow Cytometry Human
Tannetta D, Dragovic R, Gardiner C, Redman C, Sargent I Characterisation of syncytiotrophoblast vesicles in normal pregnancy and pre-eclampsia: expression of Flt-1 and endoglin. PLoS ONE, 2013-02-20;8(2):e56754. 2013-02-20 [PMID: 23437230] (Flow Cytometry, Human) Flow Cytometry Human
de Groot JF, Piao Y, Tran H, Gilbert M, Wu HK, Liu J, Bekele BN, Cloughesy T, Mehta M, Robins HI, Lassman A, Deangelis L, Camphausen K, Chen A, Yung W, Prados M, Wen PY, Heymach JV Myeloid Biomarkers Associated with Glioblastoma Response to Anti-VEGF Therapy with Aflibercept. Clin. Cancer Res., 2011-06-01;17(14):4872-4881. 2011-06-01 [PMID: 21632852] (Flow Cytometry, Human) Flow Cytometry Human
Xiong YQ, Sun HC, Zhang W Human hepatocellular carcinoma tumor-derived endothelial cells manifest increased angiogenesis capability and drug resistance compared with normal endothelial cells. Clin. Cancer Res., 2009-07-28;15(15):4838-46. 2009-07-28 [PMID: 19638466] (Flow Cytometry, Human) Flow Cytometry Human
Norden-Zfoni A, Desai J, Manola J, Beaudry P, Force J, Maki R, Folkman J, Bello C, Baum C, DePrimo SE, Shalinsky DR, Demetri GD, Heymach JV Blood-based biomarkers of SU11248 activity and clinical outcome in patients with metastatic imatinib-resistant gastrointestinal stromal tumor. Clin. Cancer Res., 2007-05-01;13(9):2643-50. 2007-05-01 [PMID: 17473195] (Flow Cytometry, Human) Flow Cytometry Human

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Bioinformatics

Gene Symbol FLT1
Uniprot