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VEGFR1/Flt-1 Antibody (141522) [PE/Cy5.5]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow
Clone
141522
Clonality
Monoclonal
Host
Rat
Conjugate
PE/Cy5.5

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB4711U-100UG
Alexa Fluor 405
FAB4711V-100UG
Alexa Fluor 488
FAB4711G
Alexa Fluor 532
FAB4711X
Alexa Fluor 594
FAB4711T-100UG
Alexa Fluor 647
FAB4711R-100UG
Alexa Fluor 700
FAB4711N-100UG
Alexa Fluor 750
FAB4711S-100UG
Allophycocyanin
FAB4711A
Allophycocyanin/Cy7
FAB4711APCCY7
Biotin
FAB4711B
DyLight 350
FAB4711D
DyLight 405
FAB4711E
DyLight 488
FAB4711K
DyLight 550
FAB4711L
DyLight 594
FAB4711M
DyLight 650
FAB4711W
DyLight 680
FAB4711Y
DyLight 755
FAB4711Z
HRP
FAB4711H
Janelia Fluor 525
FAB4711JF525
Janelia Fluor 549
FAB4711I
Janelia Fluor 646
FAB4711J
Janelia Fluor 669
FAB4711JF669
PE/Atto594
FAB4711PEATT594
PE/Cy7
FAB4711PECY7
PerCP
FAB4711C
Phycoerythrin
FAB4711P
Unconjugated
MAB4711
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB4711
Carrier Free
FAB4711N-100UG
Carrier Free
FAB4711P
Carrier Free
FAB4711A
Carrier Free
FAB4711G
Carrier Free
MAB4711
Carrier Free
MAB4711-SP
Carrier Free
FAB4711V-100UG
Carrier Free
FAB4711U-100UG
Carrier Free
FAB4711T-100UG
Carrier Free
FAB4711S-100UG
Carrier Free
FAB4711R-100UG
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VEGFR1/Flt-1 Antibody (141522) [PE/Cy5.5] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse VEGFR1/Flt‑1
Ser27-Glu759
Accession # P35969
Specificity
Detects mouse VEGFR1/Flt‑1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human VEGFR1, recombinant mouse (rm) VEGFR2, or rmVEGFR3 is observed.
Isotype
IgG2b
Clonality
Monoclonal
Host
Rat
Gene
FLT1
Purity
Protein A or G purified from hybridoma culture supernatant
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Applications/Dilutions

Dilutions
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined. For optimal results using our Tandem dyes, please avoid prolonged exposure to light or extreme temperature fluctuations. These can lead to irreversible degradation or decoupling. When staining intracellular targets, specific attention to the fixation and permeabilization steps in your flow protocol may be required. Please contact our technical support team at technical@novusbio.com if you have any questions.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Alternate Names for VEGFR1/Flt-1 Antibody (141522) [PE/Cy5.5]

  • EC 2.7.10
  • EC 2.7.10.1
  • FLT
  • FLT1
  • Flt-1
  • Fms-like tyrosine kinase 1
  • fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascularpermeability factor receptor)
  • FRT
  • Tyrosine-protein kinase FRT
  • Tyrosine-protein kinase receptor FLT
  • vascular endothelial growth factor receptor 1
  • Vascular permeability factor receptor
  • VEGF R1
  • VEGFR1
  • VEGFR-1

Background

Receptors for VEGF, VEGFB and PGF have tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. VEGF and its high-affinity binding receptors--the tyrosine kinases FLK1 and FLT1--are thought to be important for the development of embryonic vasculature. It has been shown that an alternately spliced form of FLT1 produces a soluble protein, termed sFLT1, which binds vascular endothelial growth factor with high affinity, playing an inhibitory role in angiogenesis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol FLT1