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VE-Statin/EGFL7 Antibody [Biotin]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Goat
Conjugate
Biotin
Concentration
LYOPH

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Catalog# & Conjugate Size Price
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VE-Statin/EGFL7 Antibody [Biotin] Summary

Immunogen
E. coli-derived recombinant mouse VE‑Statin Isoform 1
Thr21-Leu275
Accession # Q9QXT5
Specificity
Detects mouse VE‑Statin Isoform 1 in Western blots. In Western blots, approximately 10% cross-reactivity with recombinant human VE‑Statin is observed.
Source
N/A
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
EGFL7
Purity Statement
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for VE-Statin/EGFL7 Antibody [Biotin]

  • EGFL7
  • EGF-like protein 7
  • EGF-like-domain, multiple 7
  • epidermal growth factor-like protein 7
  • MEGF7
  • MGC111117
  • Multiple EGF-like domains protein 7
  • Multiple epidermal growth factor-like domains protein 7
  • NEU1 protein
  • NOTCH4-like protein
  • RP11-251M1.2
  • Vascular endothelial statin
  • VEStatin
  • VE-Statin
  • ZNEU1

Background

VE-Statin, also known as epidermal growth factor-like domain 7 (EGFL7), is a secreted endothelial-specific protein that is a marker for progenitor, embryonic and adult endothelial cells. Mature soluble VE-Statin is a 30‑32 kDa protein containing an N-terminal cysteine-rich EMI domain, followed by two EGF-like domains and a coiled‑coil region. Two isoforms of mouse VE-Statin have been reported. Isoform 2 shows a deletion of 13 amino acid residues between residues 236 to 248 of isoform 1. VE-Statin inhibits PDGF-BB-induced smooth muscle cell migration. The amino acid sequence of mouse VE-Statin is 76% and 80% identical to that of canine and human VE-Statin, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol EGFL7
Uniprot