VE-Statin/EGFL7 Antibody [Biotin] Summary
Immunogen |
E. coli-derived recombinant mouse VE‑Statin Isoform 1 Thr21-Leu275 Accession # Q9QXT5 |
Specificity |
Detects mouse VE‑Statin Isoform 1 in Western blots. In Western blots, approximately 10% cross-reactivity with recombinant human VE‑Statin is observed. |
Source |
N/A |
Isotype |
IgG |
Clonality |
Polyclonal |
Host |
Goat |
Gene |
EGFL7 |
Purity Statement |
Antigen Affinity-purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Packaging, Storage & Formulations
Storage |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. - 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
|
Buffer |
Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein. |
Preservative |
No Preservative |
Concentration |
LYOPH |
Reconstitution Instructions |
Reconstitute at 0.2 mg/mL in sterile PBS. |
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for VE-Statin/EGFL7 Antibody [Biotin]
Background
VE-Statin, also known as epidermal growth factor-like domain 7 (EGFL7), is a secreted endothelial-specific protein that is a marker for progenitor, embryonic and adult endothelial cells. Mature soluble VE-Statin is a 30‑32 kDa protein containing an N-terminal cysteine-rich EMI domain, followed by two EGF-like domains and a coiled‑coil region. Two isoforms of mouse VE-Statin have been reported. Isoform 2 shows a deletion of 13 amino acid residues between residues 236 to 248 of isoform 1. VE-Statin inhibits PDGF-BB-induced smooth muscle cell migration. The amino acid sequence of mouse VE-Statin is 76% and 80% identical to that of canine and human VE-Statin, respectively.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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