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UVSSA Antibody

Images

 
Western Blot: UVSSA Antibody [NBP1-32598] - Sample(30ug whole cell lysate)A: 293TB: A431 C: H1299D: HeLa S3 E: Hep G2 F: MOLT4 G: Raji 7. 5% SDS PAGE, antibody diluted at 1:1000.
Immunocytochemistry/ Immunofluorescence: UVSSA Antibody [NBP1-32598] - Paraformaldehyde-fixed A431, using antibody at 1:200 dilution.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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UVSSA Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the N-terminus region of human UVSSA. The exact sequence is proprietary.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
UVSSA
Purity
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 1:100-1:1000
  • Western Blot 1:500-1:3000
Theoretical MW
81 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Publications
Read Publications using
NBP1-32598 in the following applications:

  • WB
    2 publications

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (83%), Rat (83%).

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol
Preservative
0.01% Thimerosal
Purity
Antigen Affinity-purified

Alternate Names for UVSSA Antibody

  • hypothetical protein LOC57654
  • KIAA1530
  • MGC117169

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Publications for UVSSA Antibody (NBP1-32598)(7)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: WB.


Filter By Application
WB
(2)
All Applications
Filter By Species
Human
(3)
All Species
Showing Publications 1 - 7 of 7.
Publications using NBP1-32598 Applications Species
Y van der We, H Golan-Berm, TET Mevissen, K Apelt, R González-P, J Goedhart, EE Heilbrun, ACO Vertegaal, D van den He, JC Walter, S Adar, MS Luijsterbu The cooperative action of CSB, CSA, and UVSSA target TFIIH to DNA damage-stalled RNA polymerase II Nat Commun, 2020-04-30;11(1):2104. 2020-04-30 [PMID: 32355176]
Schwertman P, Lagarou A, Dekkers DH et al. UV-sensitive syndrome protein UVSSA recruits USP7 to regulate transcription-coupled repair. Nat Genet 2012-05-01 [PMID: 22466611] (WB, Human) WB Human
Nakazawa Y, Sasaki K, Mitsutake N et al. Mutations in UVSSA cause UV-sensitive syndrome and impair RNA polymerase IIo processing in transcription-coupled nucleotide-excision repair. Nat Genet. 2012-04-01 [PMID: 22466610] (Human) Human
van der Weegen Y, Berman HG, Mevissen TET, Apelt K The sequential and cooperative action of CSB, CSA and UVSSA targets the TFIIH complex to DNA damage-stalled RNA polymerase II bioRxiv (WB, Human) WB Human
Sato M, Liebau AW, Liu Z, et al. The UVSSA complex alleviates MYC-driven transcription stress The Journal of cell biology 2021-02-01 [PMID: 33404608]
Weegen Y Unravelling molecular mechanisms in transcription-coupled nucleotide excision repair Thesis 2022-01-01
van der Weegen Y, Berman HG, Mevissen TET, Apelt K The sequential and cooperative action of CSB, CSA and UVSSA targets the TFIIH complex to DNA damage-stalled RNA polymerase II Nat Commun 2020-11-07 [PMID: 33159085]

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Bioinformatics

Gene Symbol UVSSA
Entrez
Uniprot