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TRERF1 Antibody [DyLight 488]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 488

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TRERF1 Antibody [DyLight 488] Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 1150 and 1200 of human transcriptional regulating protein 132 (transcriptional regulating factor 1) using the numbering given in entry NP_277037.1 (GeneID 55809).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TRERF1
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for TRERF1 Antibody [DyLight 488]

  • BCAR2
  • Breast cancer estrogen resistance 2RAPAHSA277276
  • dJ139D8.5
  • FLJ21198
  • rapa-1
  • rapa-2
  • RP1-139D8.5
  • transcriptional regulating factor 1
  • transcriptional regulating protein 132
  • transcriptional-regulating factor 1
  • Transcriptional-regulating protein 132
  • TREP132
  • TReP-132
  • Zinc finger protein rapa
  • Zinc finger transcription factor TReP-132

Background

The transcriptional regulating protein of 132 kDa (TReP-132/TRERF1) was identified as a transcription factor that interacts with and activates the promoter of the CYP11A1 gene, a gene that encodes cytochrome P450 side chain cleavage (P450scc) and catalyzes the first step in steroidgenesis. TRep-132 can function as a nuclear receptor co-activator and has been shown to interact with Sp1 and the progesterone receptor (PR) to suppress growth via activation of the gene promoters of the cyclin-dependent kinase inhibitors, p21 and p27.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

WB Video Protocol

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Bioinformatics

Gene Symbol TRERF1