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Human TRAILR1/TNFRSF10A ELISA Kit (Colorimetric)

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ELISA: Human TRAILR1/TNFRSF10A ELISA Kit (Colorimetric) [NBP3-14636] - Example of Human TRAILR1/TNFRSF10A Standard Curve.
ELISA: Human TRAILR1/TNFRSF10A ELISA Kit (Colorimetric) [NBP3-14636] - Example of Human TRAILR1/TNFRSF10A Standard Curve.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Suitable Sample Type
Serum, Cell lysates, Cell culture supernatant
Standard Curve Range
31.25-1000 pg/ml
Sensitivity
8 pg/ml

Order Details

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Human TRAILR1/TNFRSF10A ELISA Kit (Colorimetric) Summary

Description
Incubation: 2 hours 30 minutes
Specificity
Specific for human TRAILR1/TNFRSF10A. No cross reactivity observed with TRAIL, CD117, IL-6R, IL-2R, CD116, TRAIL R2, TRAIL R3, TRAIL R4, CD178 and Granzyme B..
Standard Curve Range
31.25-1000 pg/ml
Sensitivity
8 pg/ml
Assay Type
Sandwich ELISA
Inter-Assay
CV% < 13.87
Intra-Assay
CV% < 7.57
Spike Recovery
81 to 113%
Sample Volume
100 ul
Kit Type
ELISA Kit (Colorimetric)
Gene
TNFRSF10A

Applications/Dilutions

Dilutions
  • ELISA

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.

Kit Components

Components
  1. Biotinylated secondary antibody
  2. Buffers
  3. Controls (where applicable)
  4. Detailed procedure.
  5. Pre-coated strip plates
  6. Standards
  7. Stop reagents
  8. Streptavidin-HRP
  9. TMB

Alternate Names for Human TRAILR1/TNFRSF10A ELISA Kit (Colorimetric)

  • APO2
  • CD261 antigen
  • CD261
  • cytotoxic TRAIL receptor
  • Death receptor 4
  • DR4 TRAIL receptor 1
  • DR4
  • TNF-related apoptosis inducing ligand receptor 1
  • TNF-related apoptosis-inducing ligand receptor 1
  • TNFRSF10A
  • TRAIL R1
  • TRAILR1
  • TRAIL-R1
  • TRAILR-1
  • TRAILR1MGC9365
  • tumor necrosis factor receptor superfamily member 10A
  • tumor necrosis factor receptor superfamily, member 10a

Background

TRAIL-R1 (CD261, DR4) is a type I transmembrane protein, also called TRAIL receptor 1. The ligand for this DR4 death receptor has been identified and termed TRAIL, which is a member of the TNF family. DR4, as many other receptors (Fas, TNFR1, etc.), mediates apoptosis and NF kappaB activation in many cells and tissues. Apoptosis, a programmed cell death, is a operating process in normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by coupled of certain cytokines (TNF family - TNF, Fas ligand) and their death domain containing receptors (TNFR1, Fas receptor).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

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  Safety datasheet
  Manual - NBP3-14636
  PDF Datasheet
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Bioinformatics

Gene Symbol TNFRSF10A