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TIM-1/KIM-1/HAVCR Antibody (219211) [DyLight 405]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow, IHC, CyTOF-ready
Clone
219211
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 405

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TIM-1/KIM-1/HAVCR Antibody (219211) [DyLight 405] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human TIM‑1/KIM-1/HAVCR
Ser21-Thr288
Accession # AAC39862
Specificity
Detects human TIM‑1/KIM-1/HAVCR in direct ELISAs and Western blots. Does not cross-react with recombinant mouse (rm) TIM-1, rmTIM-2, or rhTIM-3.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
HAVCR1
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
  • Immunohistochemistry
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for TIM-1/KIM-1/HAVCR Antibody (219211) [DyLight 405]

  • CD365
  • HAVCR1
  • HAVCR-1
  • HAVCRT cell immunoglobin domain and mucin domain protein 1
  • hepatitis A virus cellular receptor 1
  • Kidney injury molecule 1
  • KIM1
  • KIM-1
  • T-cell immunoglobulin and mucin domain-containing protein 1
  • TIM1
  • TIM-1
  • TIM-1TIM
  • TIM1TIMD-1
  • TIMD1T-cell membrane protein 1

Background

TIM 1 is a transmembrane protein containing immunoglobulin domain and mucin-like domain; it is developmentally expressed at very high levels in the blastocyst. TIM 1 binds hepatitis virus in humans and is expressed on activated CD4+ lymphocytes especially on Th2 cells and has been implicated to play a critical role in the development of atopic disease (in particular airway hyperreactivity) and other Th2-biased immune responses.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol HAVCR1