Western Blot: Thioredoxin Reductase 1/TRXR1 Antibody (30F1) [NBP2-59489] - Lane 1: HeLa cell lysates, Lane 2: A549 cell lysates, Lane 3: PC3 cell lysates
Immunocytochemistry/ Immunofluorescence: Thioredoxin Reductase 1/TRXR1 Antibody (30F1) [NBP2-59489] - Analysis of TXNRD1 in Hep3B cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human ...read more
Gene associated with retinoic and IFN-induced mortality 12 protein
Gene associated with retinoic and interferon-induced mortality 12 protein
GRIM12
GRIM-12
GRIM-12TR1
KDRF
KM-102-derived reductase-like factor
MGC9145
oxidoreductase
Thioredoxin Reductase 1
thioredoxin reductase 1, cytoplasmic
thioredoxin reductase GRIM-12
Thioredoxin reductase TR1
TR
TR1
TRXR1
TRXRD1
TXNR
TXNRD1
TXNRTRXR1
Background
thioredoxin reductase 1 is a pyridine nucleotide oxidoreductase which reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. It is thought to function as a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine residue which is required for the catalytic activity. Alternative splicing results in several transcript variants encoding the same protein. Additional transcript variants have been described but their biological validity has not been determined.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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