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TFEC Antibody

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Western Blot: TFEC Antibody [NB100-1031] - (1ug/ml) of Human Testis lysate (RIPA buffer, 30ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

TFEC Antibody Summary

Immunogen
Peptide with sequence TLDHQIINPTLK-C corresponding to N-Terminus according to NP_036384.1, NP_001018068.1.
Specificity
This antibody is expected to recognise both reported Human isoforms according to NP_036384.1 and NP_001018068.1.
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
TFEC
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Peptide ELISA Detection limit 1:32000
  • Western Blot 0.5 - 2 ug/ml
Application Notes
WB: Approx. 40-45 kDa band observed in human testis lysate.
Control
Human Testis Whole Tissue Lysate (Adult Whole Normal)
Publications
Read Publications using NB100-1031.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for TFEC Antibody

  • Class E basic helix-loop-helix protein 34
  • hTFEC-L
  • TCFECTFECLbHLHe34BHLHE34
  • TFE-C
  • transcription factor EC
  • Transcription factor EC-like

Background

Transcriptional regulator that acts as a repressor or an activator. Acts as a transcriptional repressor on minimal promoter containing element F (that includes an E-box sequence). Binds to element F in an E-box sequence-specific manner. Acts as a transcriptional transactivator on the proximal promoter region of the tartrate-resistant acid phosphatase (TRAP) E-box containing promoter . Collaborates with MITF in target gene activation . Acts as a transcriptional repressor on minimal promoter containing mu E3 enhancer sequence . Binds to mu E3 DNA sequence of the immunoglobulin heavy-chain gene enhancer . Binds DNA in a homo- or heterodimeric form

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for TFEC Antibody (NB100-1031)(3)

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Product General Protocols

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Video Protocols

WB Video Protocol

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Bioinformatics

Gene Symbol TFEC
Entrez
Uniprot