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Recombinant Human Tau 441 Active, P301S Mutant, Pre-formed Fibrils Protein [Atto488]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Func, PAGE
Conjugate
Atto488

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Unconjugated
NBP2-76794-100ug
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Recombinant Human Tau 441 Active, P301S Mutant, Pre-formed Fibrils Protein [Atto488] Summary

Description
A full length recombinant protein of Human Tau 441

Source: E. coli

Uniprot ID: P10636

Amino Acid Sequence: MAEPRQEFEV MEDHAGTYGL GDRKDQGGYT MHQDQEGDTD AGLKESPLQT PTEDGSEEPG SETSDAKSTP TAEDVTAPLV DEGAPGKQAA AQPHTEIPEG TTAEEAGIGD TPSLEDEAAG HVTQARMVSK SKDGTGSDDK KAKGADGKTK IATPRGAAPP GQKGQANATR IPAKTPPAPK TPPSSGEPPK SGDRSGYSSP GSPGTPGSRS RTPSLPTPPT REPKKVAVVR TPPKSPSSAK SRLQTAPVPM PDLKNVKSKI GSTENLKHQP GGGKVQIINK KLDLSNVQSK CGSKDNIKHVSGGGSVQIVY KPVDLSKVTS KCGSLGNIHH KPGGGQVEVK SEKLDFKDRV QSKIGSLDNI THVPGGGNKK IETHKLTFRE NAKAKTDHGA EIVYKSPVVS GDTSPRHLSN VSSTGSIDMV DSPQLATLAD EVSASLAKQG L
Localization
Cytoplasm, Axolemma, Axolemma Plasma Membrane, Axon, Cell Body, Cell membrane, Cytoplasmic Ribonucleoprotein Granule, Cytoplasmic Side, Cytoskeleton, Cytosol, Dendrite, Growth cone, Microtubule, Microtubule Associated Complex, Neurofibrillary Tangle, Neuronal Cell Body, Nuclear Periphery, Nuclear Speck, Nucleus, Peripheral membrane protein, Plasma Membrane, Tubulin Complex
Preparation
Method
Ion-exchange Purified
Details of Functionality
Thioflavin T emission curve shows increased fluorescence (correlated to protein fibrillation) when active Tau 441 pre-formed fibrils ATTO-594 are combined with active Tau 441 monomers.
Protein/Peptide Type
Recombinant Protein
Gene
MAPT
Purity
>95%

Applications/Dilutions

Dilutions
  • In vitro assay
  • In vivo assay
  • SDS-Page
  • Western Blot

Packaging, Storage & Formulations

Storage
Store at -80C. Avoid freeze-thaw cycles.
Buffer
PBS pH 7.4
Preservative
0.09% Sodium Azide
Purity
>95%

Notes

Please note that the 200ug and 500ug sizes are sent in 2x100ug and 5x100ug vials, respectively

Alternate Names for Recombinant Human Tau 441 Active, P301S Mutant, Pre-formed Fibrils Protein [Atto488]

  • MAPT
  • microtubule-associated protein tau
  • MTBT1
  • MTBT2

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol MAPT