Sulfamidase/SGSH Antibody

Also known as N-sulfoglucosamine sulfohydrolase and heparan N-sulfatase, Sulfamidase/SGSH is an important member of the sulfatase family involved in the degradation of heparan sulfate (1). The SGSH deficiency results in mucopolysaccharidosis type IIIA (MPS IIIA, Sanfilippo A syndrome), an autosomal recessive lysosomal storage disease characterized by neurological dysfunction but relatively mild somatic manifestations (2). The deduced amino acid sequence of mouse SGSH consists of a signal peptide (residues 1‑22) and a mature chain (residues 23‑502) (1). rmSGSH corresponds to the mature chain and has sulfatase activity.

• Sulfamidase/SGSH Antibodies
• Sulfamidase/SGSH ELISA Kits
• Sulfamidase/SGSH Lysate
• Sulfamidase/SGSH Proteins
• Sulfamidase/SGSH Proteins and Enzymes