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STAT3 Antibody (232209) [DyLight 550]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, IP, Flow, ICC/IF, KO
Clone
232209
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 550

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
IC1799U-100UG
Alexa Fluor 405
IC1799V-100UG
Alexa Fluor 488
IC1799G-100UG
Alexa Fluor 532
FAB1799X
Alexa Fluor 594
IC1799T-100UG
Alexa Fluor 647
IC1799R-100UG
Alexa Fluor 700
IC1799N-100UG
Alexa Fluor 750
IC1799S-100UG
Allophycocyanin
FAB1799A
Biotin
FAB1799B
CoraFluor 1
FAB1799CL1
DyLight 350
FAB1799D
DyLight 405
FAB1799E
DyLight 488
FAB1799K
DyLight 594
FAB1799M
DyLight 650
FAB1799W
DyLight 680
FAB1799Y
DyLight 755
FAB1799Z
Fluorescein
IC1799F
HRP
FAB1799H
Janelia Fluor 525
FAB1799JF525
Janelia Fluor 549
FAB1799I
Janelia Fluor 585
FAB1799JF585
Janelia Fluor 635
FAB1799JF635
Janelia Fluor 646
FAB1799J
Janelia Fluor 669
FAB1799JF669
PerCP
FAB1799C
Phycoerythrin
IC1799P
Unconjugated
MAB1799
mFluor Violet 450 SE
FAB1799MFV450
mFluor Violet 500 SE
FAB1799MFV500
mFluor Violet 610 SE
FAB1799MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB1799
Carrier Free
IC1799P
Carrier Free
MAB1799
Carrier Free
IC1799F
Carrier Free
MAB1799-SP
Carrier Free
IC1799V-100UG
Carrier Free
IC1799U-100UG
Carrier Free
IC1799T-100UG
Carrier Free
IC1799S-100UG
Carrier Free
IC1799R-100UG
Carrier Free
IC1799N-100UG
Carrier Free
IC1799G-100UG
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STAT3 Antibody (232209) [DyLight 550] Summary

Immunogen
E. coli-derived recombinant human STAT3
Met1-Asn175
Accession # P40763
Specificity
Detects human, mouse, and rat STAT3 in Western blots.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
STAT3
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Immunocytochemistry
  • Immunoprecipitation
  • Intracellular Staining by Flow Cytometry
  • Knockout Validated
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for STAT3 Antibody (232209) [DyLight 550]

  • Acute-phase response factor
  • APRFMGC16063
  • DNA-binding protein APRF
  • FLJ20882
  • HIES
  • signal transducer and activator of transcription 3 (acute-phase responsefactor)
  • signal transducer and activator of transcription 3
  • STAT3

Background

Stat3 is a member of a group of proteins (Signal Transduction and Activators of Transcription) that act as both signal transducers for cytokines and growth factors, as well as transcription factors (1,2). Stats are activated by tyrosine phosphorylation in response to different ligands, after which they translocate to the cell nucleus (1). Stat3 is constitutively activated in a number of human tumors (3). Stat3 is activated by phosphorylation on tyrosine 705 which induces dimerization, nuclear translocation, and DNA binding While, Stat3-activated transcription seems to be regulated by serine phosphorylation at serine 727 (4)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol STAT3