Name: ST6 Gal Sialyltransferase 1/ST6GAL1/CD75 Antibody [Unconjugated]
Brand: Novus Biologicals
SKU: AF5924
Price: 489 USD

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At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

Reactivity	HuSpecies Glossary
Applications	WB, Simple Western, IHC, ICC/IF
Clonality	Polyclonal
Host	Goat
Conjugate	Unconjugated
Concentration	LYOPH

Conjugate	Catalog #	Availability	Size	Price
Biotin	BAF5924

Immunogen	Mouse myeloma cell line NS0-derived recombinant human ST6 Gal Sialyltransferase 1/ST6GAL1 Lys27-Cys406 Accession # P15907
Specificity	Detects human ST6 Gal Sialyltransferase 1/ST6GAL1 in direct ELISAs and Western blots.
Source	N/A
Isotype	IgG
Clonality	Polyclonal
Host	Goat
Gene	ST6GAL1
Purity Statement	Antigen Affinity-purified
Innovator's Reward	Test in a species/application not listed above to receive a full credit towards a future purchase. Learn about the Innovator's Reward

Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer	Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative	No Preservative
Concentration	LYOPH
Reconstitution Instructions	Reconstitute at 0.2 mg/mL in sterile PBS.

ST6 Gal Sialyltransferase 1/ST6GAL1/CD75 Antibody [Unconjugated]

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ST6 Gal Sialyltransferase 1/ST6GAL1/CD75 Antibody [Unconjugated] Summary

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Publications for ST6 Gal Sialyltransferase 1/ST6GAL1/CD75 Antibody (AF5924)(30)

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Bioinformatics

Publications using AF5924	Applications	Species
Kosmicki, JA;Marcketta, A;Sharma, D;Di Gioia, SA;Batista, S;Yang, XM;Tzoneva, G;Martinez, H;Sidore, C;Kessler, MD;Horowitz, JE;Roberts, GHL;Justice, AE;Banerjee, N;Coignet, MV;Leader, JB;Park, DS;Lanche, R;Maxwell, E;Knight, SC;Bai, X;Guturu, H;Baltzell, A;Girshick, AR;McCurdy, SR;Partha, R;Mansfield, AJ;Turissini, DA;Zhang, M;Mbatchou, J;Watanabe, K;Verma, A;Sirugo, G;Colorado Center for Precision Medicine, ;Mayo Clinic Project Generation, ;Regeneron Genetics Center, ;University of California Los Angeles ATLAS Collaboration, ;Ritchie, MD;Salerno, WJ;Shuldiner, AR;Rader, DJ;Mirshahi, T;Marchini, J;Overton, JD;Carey, DJ;Habegger, L;Reid, JG;Economides, A;Kyratsous, C;Karalis, K;Baum, A;Cantor, MN;Rand, KA;Hong, EL;Ball, CA;Siminovitch, K;Baras, A;Abecasis, GR;Ferreira, MAR; Genetic risk factors for COVID-19 and influenza are largely distinct Nature genetics 2024-08-05 [PMID: 39103650] (Western Blot, Human)	Western Blot	Human
Dashzeveg, NK;Jia, Y;Zhang, Y;Gerratana, L;Patel, P;Shajahan, A;Dandar, T;Ramos, EK;Almubarak, HF;Adorno-Cruz, V;Taftaf, R;Schuster, EJ;Scholten, D;Sokolowski, MT;Reduzzi, C;El-Shennawy, L;Hoffmann, AD;Manai, M;Zhang, Q;D'Amico, P;Azadi, P;Colley, KJ;Platanias, LC;Shah, AN;Gradishar, WJ;Cristofanilli, M;Muller, WA;Cobb, BA;Liu, H; Dynamic glycoprotein hyposialylation promotes chemotherapy evasion and metastatic seeding of quiescent circulating tumor cell clusters in breast cancer Cancer discovery 2023-06-05 [PMID: 37272843] (Western Blot, Human)	Western Blot	Human
J Van Coilli, T Pongracz, J Rahmöller, HJ Chen, CE Geyer, LA van Vught, JS Buhre, T Šušti?, TLJ van Osch, M Steenhuis, W Hoepel, W Wang, AS Lixenfeld, J Nouta, S Keijzer, F Linty, R Visser, MD Larsen, EL Martin, I Künsting, S Lehrian, V von Kopylo, C Kern, HB Lunding, M de Winther, N van Mourik, T Rispens, T Graf, MA Slim, RP Minnaar, MK Bomers, JJ Sikkens, APJ Vlaar, CE van der Sc, J den Dunnen, M Wuhrer, M Ehlers, G Vidarsson, Fatebenefr, UMC COVID- The BNT162b2 mRNA SARS-CoV-2 vaccine induces transient afucosylated IgG1 in naive but not in antigen-experienced vaccinees EBioMedicine, 2022-12-16;87(0):104408. 2022-12-16 [PMID: 36529104] (Flow Cytometry, Human)	Flow Cytometry	Human
X Zou, J Lu, Y Deng, Q Liu, X Yan, Y Cui, X Xiao, M Fang, F Yang, H Sawaki, T Sato, B Tan, X Lu, B Feng, A Kuno, H Narimatsu, C Gao, Y Zhang ST6GAL1 inhibits metastasis of hepatocellular carcinoma via modulating sialylation of MCAM on cell surface Oncogene, 2022-12-17;0(0):. 2022-12-17 [PMID: 36528750] (IHC, Human)	IHC	Human
Natallia Makarava, Elizaveta Katorcha, Jennifer Chen-Yu Chang, Joseph T. Y. Lau, Ilia V. Baskakov Deficiency in ST6GAL1, one of the two alpha 2,6-sialyltransferases, has only a minor effect on the pathogenesis of prion disease Frontiers in Molecular Biosciences 2022-11-14 [PMID: 36452458]
S Gc, K Tuy, L Rickenback, R Jones, A Chakrabort, CR Miller, EA Beierle, VS Hanumanthu, AN Tran, JA Mobley, SL Bellis, AB Hjelmeland alpha2,6 Sialylation mediated by ST6GAL1 promotes glioblastoma growth JCI Insight, 2022-11-08;7(21):. 2022-11-08 [PMID: 36345944] (IHC, Western Blot, Human)	IHC, Western Blot	Human
NC Hait, A Maiti, R Wu, VL Andersen, CC Hsu, Y Wu, DG Chapla, K Takabe, ME Rusiniak, W Bshara, J Zhang, KW Moremen, JTY Lau Extracellular sialyltransferase st6gal1 in breast tumor cell growth and invasiveness Cancer Gene Therapy, 2022-06-08;0(0):. 2022-06-08 [PMID: 35676533] (Western Blot, Human)	Western Blot	Human
Mingfeng Zhang, Tong Qi, Lu Yang, Daniel Kolarich, Nora Heisterkamp Multi-Faceted Effects of ST6Gal1 Expression on Precursor B-Lineage Acute Lymphoblastic Leukemia Frontiers in Oncology 2022-03-16 [PMID: 35371997]
M Smithson, R Irwin, G Williams, KL Alexander, LE Smythies, M Nearing, MC McLeod, S Al Diffalh, SL Bellis, KM Hardiman Sialyltransferase ST6GAL-1 mediates resistance to chemoradiation in rectal cancer The Journal of Biological Chemistry, 2022-01-15;0(0):101594. 2022-01-15 [PMID: 35041825] (IHC, Western Blot, Human)	IHC, Western Blot	Human
AT Holdbrooks, KE Ankenbauer, J Hwang, SL Bellis Regulation of inflammatory signaling by the ST6Gal-I sialyltransferase PLoS ONE, 2020-11-09;15(11):e0241850. 2020-11-09 [PMID: 33166339] (Western Blot, Mouse)	Western Blot	Mouse
CM Britain, N Bhalerao, AD Silva, A Chakrabort, DJ Buchsbaum, MR Crowley, DK Crossman, YJK Edwards, SL Bellis Glycosyltransferase ST6Gal-I promotes the epithelial to mesenchymal transition in pancreatic cancer cells J Biol Chem, 2020-11-23;0(0):. 2020-11-23 [PMID: 33148698] (Western Blot, Human)	Western Blot	Human
KL Alexander, CA Serrano, A Chakrabort, M Nearing, LN Council, A Riquelme, M Garrido, SL Bellis, LE Smythies, PD Smith Modulation of glycosyltransferase ST6Gal-I in gastric cancer-derived organoids disrupts homeostatic epithelial cell turnover J. Biol. Chem., 2020-08-06;0(0):. 2020-08-06 [PMID: 32763973] (ICC, IHC, Human)	ICC, IHC	Human
L Ou, X He, N Liu, Y Song, J Li, L Gao, X Huang, Z Deng, X Wang, S Lin Sialylation of FGFR1 by ST6Gal?I overexpression contributes to ovarian cancer cell migration and chemoresistance Mol Med Rep, 2020-01-20;21(3):1449-1460. 2020-01-20 [PMID: 32016470] (Western Blot, Human)	Western Blot	Human
KA Dorsett, RB Jones, KE Ankenbauer, AB Hjelmeland, SL Bellis Sox2 promotes expression of the ST6Gal-I glycosyltransferase in ovarian cancer cells J Ovarian Res, 2019-10-14;12(1):93. 2019-10-14 [PMID: 31610800] (Western Blot, Human)	Western Blot	Human
Q Zhang, JN Higginboth, DK Jeppesen, YP Yang, W Li, ET McKinley, R Graves-Dea, J Ping, CM Britain, KA Dorsett, CL Hartman, DA Ford, RM Allen, KC Vickers, Q Liu, JL Franklin, SL Bellis, RJ Coffey Transfer of Functional Cargo in Exomeres Cell Rep, 2019-04-04;0(0):. 2019-04-04 [PMID: 30956133] (Western Blot, Human)	Western Blot	Human
Zhou X, Kinlough CL, Hughey RP et al. Sialylation of MUC4b N-glycans by ST6GAL1 orchestrates human airway epithelial cell differentiation associated with Type-2 inflammation JCI Insight 2/7/2019 [PMID: 30730306]
J Mayr, K Lau, JCC Lai, IA Gagarinov, Y Shi, S McAtamney, RWY Chan, J Nicholls, M von Itzste, T Haselhorst Unravelling the Role of O-glycans in Influenza A Virus Infection Sci Rep, 2018-11-06;8(1):16382. 2018-11-06 [PMID: 30401951] (ICC, Human)	ICC	Human
MA Schulz, W Tian, Y Mao, J Van Coilli, L Sun, JS Larsen, YH Chen, C Kristensen, SY Vakhrushev, H Clausen, Z Yang Glycoengineering design options for IgG1 in CHO cells using precise gene editing Glycobiology, 2018-07-01;0(0):. 2018-07-01 [PMID: 29596681] (ICC, Hamster)	ICC	Hamster
RB Jones, KA Dorsett, AB Hjelmeland, SL Bellis The ST6Gal-I sialyltransferase protects tumor cells against hypoxia by enhancing HIF-1? signaling J. Biol. Chem., 2018-02-23;0(0):. 2018-02-23 [PMID: 29475939] (Western Blot, Human)	Western Blot	Human
CM Britain, AT Holdbrooks, JC Anderson, CD Willey, SL Bellis Sialylation of EGFR by the ST6Gal-I sialyltransferase promotes EGFR activation and resistance to gefitinib-mediated cell death J Ovarian Res, 2018-02-05;11(1):12. 2018-02-05 [PMID: 29402301] (Western Blot, Human)	Western Blot	Human
AT Holdbrooks, CM Britain, SL Bellis ST6Gal-I sialyltransferase promotes tumor necrosis factor (TNF)-mediated cancer cell survival via sialylation of the TNF receptor 1 (TNFR1) death receptor J. Biol. Chem., 2017-12-12;0(0):. 2017-12-12 [PMID: 29233887] (Western Blot, Human)	Western Blot	Human
A Chakrabort, KA Dorsett, HQ Trummell, ES Yang, PG Oliver, JA Bonner, DJ Buchsbaum, SL Bellis ST6Gal-I sialyltransferase promotes chemoresistance in pancreatic ductal adenocarcinoma by abrogating gemcitabine-mediated DNA damage J. Biol. Chem., 2017-11-30;0(0):. 2017-11-30 [PMID: 29191829] (Western Blot, Human)	Western Blot	Human
Mark B Jones B-cell-independent sialylation of IgG Proc Natl Acad Sci USA, 2016-06-14;113(26):7207-12. 2016-06-14 [PMID: 27303031] (IHC-Fr, Mouse)	IHC-Fr	Mouse
The tumor-associated glycosyltransferase ST6Gal-I regulates stem cell transcription factors and confers a cancer stem cell phenotype Cancer Res, 2016-05-23;0(0):. 2016-05-23 [PMID: 27216178] (IHC-P, Western Blot, Human)	IHC-P, Western Blot	Human
Yu-Chieh Wang, Jason W. Stein, Candace L. Lynch, Ha T. Tran, Chia-Yao Lee, Ronald Coleman et al. Glycosyltransferase ST6GAL1 contributes to the regulation of pluripotency in human pluripotent stem cells Scientific Reports 2015-08-25 [PMID: 26304831]
OSAMU SUZUKI, MASAFUMI ABE, YUKO HASHIMOTO Sialylation by beta -galactoside alpha -2,6-sialyltransferase and N-glycans regulate cell adhesion and invasion in human anaplastic large cell lymphoma International Journal of Oncology 2015-03-01 [PMID: 25573487]
Suzuki O, Abe M Galectin-1-mediated cell adhesion, invasion and cell death in human anaplastic large cell lymphoma: regulatory roles of cell surface glycans. Int J Oncol, 2014-03-04;44(5):1433-42. 2014-03-04 [PMID: 24589677] (ICC, Human)	ICC	Human
Shohei Ogata, Chisato Shimizu, Alessandra Franco, Ranim Touma, John T. Kanegaye, Biswa P. Choudhury et al. Treatment Response in Kawasaki Disease Is Associated with Sialylation Levels of Endogenous but Not Therapeutic Intravenous Immunoglobulin G PLoS ONE 2013-12-06 [PMID: 24324693]
Schultz , Matthew, Swindall , Amanda F, Wright , John W, Sztul , Elizabet, Landen , Charles, Bellis , Susan L ST6Gal-I sialyltransferase confers cisplatin resistance in ovarian tumor cells. J Ovarian Res, 2013-04-11;6(1):25. 2013-04-11 [PMID: 23578204] (ICC, Western Blot, Human)	ICC, Western Blot	Human
Swindall A, Londono-Joshi A, Schultz M, Fineberg N, Buchsbaum D, Bellis S ST6Gal-I protein expression is upregulated in human epithelial tumors and correlates with stem cell markers in normal tissues and colon cancer cell lines. Cancer Res, 2013-01-28;73(7):2368-78. 2013-01-28 [PMID: 23358684] (IHC, Western Blot, Human)	IHC, Western Blot	Human
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Catalog# & Formulation	Size	Price
Carrier Free AF5924-SP

Gene Symbol	ST6GAL1
Uniprot	P15907()