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SIT1 Antibody (SIT-01) [PE/Atto594]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
SIT-01
Clonality
Monoclonal
Host
Mouse
Conjugate
PE/Atto594

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SIT1 Antibody (SIT-01) [PE/Atto594] Summary

Immunogen
Bacterially produced recombinant intracellular fragment of human SIT.
Specificity
The antibody SIT-01 reacts with SHP2-interacting transmembrane adaptor protein (SIT) expressed exclusively in lymphoid organs.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
SIT1
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined. For optimal results using our Tandem dyes, please avoid prolonged exposure to light or extreme temperature fluctuations. These can lead to irreversible degradation or decoupling. When staining intracellular targets, specific attention to the fixation and permeabilization steps in your flow protocol may be required. Please contact our technical support team at technical@novusbio.com if you have any questions.

Reactivity Notes

Weak cross-reactivity with mouse.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Alternate Names for SIT1 Antibody (SIT-01) [PE/Atto594]

  • gp30/40
  • MGC125908
  • MGC125909
  • RP11-331F9.5
  • SHP2 interacting transmembrane adaptor
  • SHP2-interacting transmembrane adapter protein
  • SHP2-interacting transmembrane adaptor protein
  • signaling threshold regulating transmembrane adaptor 1
  • signaling threshold-regulating transmembrane adapter 1
  • SIT1
  • SITMGC125910
  • suppression inducing transmembrane adaptor 1
  • Suppression-inducing transmembrane adapter 1

Background

Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells. Involved in positive selection of T-cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Secondary Antibodies

 

Isotype Controls

Additional SIT1 Products

Array NB500-486PEATT594

Research Areas for SIT1 Antibody (NB500-486PEATT594)

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Blogs on SIT1

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Bioinformatics

Gene Symbol SIT1