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SH2B2 Antibody

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Western Blot: SH2B2 Antibody [NBP2-85717] - Host: Rabbit. Target Name: SH2B2. Sample Tissue: Human HepG2 Whole Cell lysates. Antibody Dilution: 1ug/ml

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.5 mg/ml

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SH2B2 Antibody Summary

Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human SH2B2. Peptide sequence: RGRDAVRESLIHVPLETFLQTLESPGGSGSDSNNTGEQGAETDPEAEPEL The peptide sequence for this immunogen was taken from within the described region.
Clonality
Polyclonal
Host
Rabbit
Gene
SH2B2
Purity
Affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1.0 ug/ml

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, 2% Sucrose
Preservative
0.09% Sodium Azide
Concentration
0.5 mg/ml
Purity
Affinity purified

Alternate Names for SH2B2 Antibody

  • adaptor protein with pleckstrin homology and src homology 2 domains
  • APSAdapter protein with pleckstrin homology and Src homology 2 domains
  • SH2 and PH domain-containing adapter protein APS
  • SH2B adapter protein 2
  • SH2B adaptor protein 2

Background

APS (adapter protein with Pleckstrin homology and Src homology 2 domains) is a member of the Lnk family, an adapter protein that is involved in B cell signaling, insulin signaling and cytoskeletal reorganization. A PH and an SH2 domain containing adapter protein that links activated tyrosine kinases to signaling pathways. It is tyrosine phosphorylated by JAK2, KIT and other kinases during B cell receptor stimulation of many different cytokines, chemokines and leukokines. APS has been shown to inhibit the JAK STAT pathway in collaboration with cCbl.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol SH2B2