Serum Amyloid A1 Antibody (SAA1cc) - BSA Free

The serum amyloid A (SAA) family comprises a number of differentially expressed lipoproteins, acute phase SAA1 and SAA2, the former being a major component in plasma, and constitutive SAA's (C-SAAs). Although the liver is the primary site of synthesis of both SAA types, extrhepatic production has been reported. The in vivo concentrations increase by as much as 1000 fold during inflammation. Several studies have expressed it's importance in the diagnosis and monitoring of various diseases. Pathological SAA values are often detected in association with normal CRP concentrations. SAA rises earlier and more sharply than CRP. SAA enhances the binding of HDL's to macrophages and thus helps the delivery of lipid to sites of injury for use in tissue repair. It is thus thought to be an integral part of the disease process. In addition, recent experiments suggest that SAA may play a "housekeeping" role in normal human tissues. Elevated levels of SAA over time predispose secondary amyloidosis, extracellular accumulation of amyloid fibrils, derived from a circulating precursor, in various tissues and organs. The most common form of amyloidosis occurs secondary to chronic inflammatory disease, particularly rheumatoid arthritis.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Monkey.

We have publications tested in 1 application: LFA.

Showing Publications 1 - 2 of 2.

Publications using NB100-73071	Applications	Species
Zhou Z, van Hooij A, Vervenne R et al. Quantitative Rapid Test for Detection and Monitoring of Active Pulmonary Tuberculosis in Nonhuman Primates Biology 2021-12-02 [PMID: 34943175]
Amaral MS, Santos DW, Pereira ASA Et al. Rhesus macaques self-curing from a schistosome infection can display complete immunity to challenge Nature communications 2021-10-26 [PMID: 34702841] (LFA, Monkey)	LFA	Monkey

Array NB100-73071

• Serum Amyloid A1 Antibodies
• Serum Amyloid A1 Lysates
• Serum Amyloid A1 Proteins
• Serum Amyloid A1 Proteins and Enzyme
• Serum Amyloid A1 ELISA