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Serpin F2/alpha 2-Antiplasmin Antibody (128) [mFluor Violet 500 SE]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications ELISA, IHC, ELISA
Clone
128
Clonality
Monoclonal
Host
Rabbit
Conjugate
mFluor Violet 500 SE

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-90459AF350
Alexa Fluor 405
NBP2-90459AF405
Alexa Fluor 488
NBP2-90459AF488
Alexa Fluor 532
NBP2-90459AF532
Alexa Fluor 594
NBP2-90459AF594
Alexa Fluor 647
NBP2-90459AF647
Alexa Fluor 700
NBP2-90459AF700
Alexa Fluor 750
NBP2-90459AF750
Allophycocyanin
NBP2-90459APC
Biotin
NBP2-90459B
CoraFluor 1
NBP2-90459CL1
DyLight 350
NBP2-90459UV
DyLight 405
NBP2-90459V
DyLight 488
NBP2-90459G
DyLight 550
NBP2-90459R
DyLight 594
NBP2-90459DL594
DyLight 650
NBP2-90459C
DyLight 680
NBP2-90459FR
DyLight 755
NBP2-90459IR
FITC
NBP2-90459F
HRP
NBP2-90459H
Janelia Fluor 525
NBP2-90459JF525
Janelia Fluor 549
NBP2-90459JF549
Janelia Fluor 585
NBP2-90459JF585
Janelia Fluor 635
NBP2-90459JF635
Janelia Fluor 646
NBP2-90459JF646
Janelia Fluor 669
NBP2-90459JF669
PE
NBP2-90459PE
PerCP
NBP2-90459PCP
Unconjugated
NBP2-90459-100ul
mFluor Violet 450 SE
NBP2-90459MFV450
mFluor Violet 610 SE
NBP2-90459MFV610
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Serpin F2/alpha 2-Antiplasmin Antibody (128) [mFluor Violet 500 SE] Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Serpin F2/alpha 2-Antiplasmin (Accession#: NP_032904.1; Met 1-Lys 491).
Specificity
No cross-reactivity in ELISA with:

Human Serpin A1 / SERPINA1 / AAT
Mouse Serpin D1 / SERPIND1 / HCF2
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
SERPINF2
Purity
Protein A purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Sandwich ELISA Capture
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Serpin F2/alpha 2-Antiplasmin Antibody (128) [mFluor Violet 500 SE]

  • AAPclade F (alpha-2 antiplasmin
  • alpha 2-Antiplasmin
  • Alpha-2-AP
  • Alpha-2-PI
  • Alpha-2-plasmin inhibitor
  • pigment epithelium derived factor), member 2
  • Serpin F2
  • serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epitheliumderived factor), member 2

Background

Identification in human milk of complexes of matriptase with ATIII, A1AT, or A2AP, provides evidence that the proteolytic activity of matriptase, from cells that express no or low levels of HAI-1, may be controlled by secreted serpins. Sequencing analysis revealed the presence of two alpha2-PI gene variations, both in the second half of exon 10: a frameshift mutation and a G to A transition at nucleotide 11337 in codon 407. Observational study of gene-disease association. (HuGE Navigator). Thrombin activatable fibrinolysis inhibitor and alpha(2)-antiplasmin are not markers for recanalization in patients with ischemic stroke treated with recombinant tissue-type plasminogen activator. Fibrinolysis is amplified by converting alpha-antiplasmin from a plasmin inhibitor to a substrate. Hydroxyethyl starch (HES) dilution enhances fibrinolysis by diminishing alpha2-antiplasmin-plasmin interactions. the Arg6Trp polymorphism may play a significant role in governing the long-term deposition/removal of intravascular fibrin. TAFIa, PAI-1 and alpha-antiplasmin: complementary roles in regulating lysis of thrombi and plasma clots. Alpha2-antiplasmin has an important role in acute pulmonary embolism. Multiple Lys residues within alpha 2-antiplasmin contribute, perhaps in a zipper-like fashion, to its binding to the in-tandem, multikringle array that configures the plasmin heavy chain. alpha2-antiplasmin induction inhibits E-cadherin processing mediated by the plasminogen activator/plasmin system, leading to suppression of progression of oral squamous cell carcinoma via upregulation of cell-cell adhesion

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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NBP2-90459MFV500
Serpin F2/alpha 2-Antiplasmin Antibody (128) [mFluor Violet 500 SE]
Species: Mu
Applications: ELISA, IHC, ELISA

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol SERPINF2