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Serpin C1/Antithrombin-III Antibody (OTI8D5) [Janelia Fluor® 549]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, Flow
Clone
OTI8D5
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 549

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-74113AF350
Alexa Fluor 405
NBP2-74113AF405
Alexa Fluor 488
NBP2-74113AF488
Alexa Fluor 532
NBP2-74113AF532
Alexa Fluor 594
NBP2-74113AF594
Alexa Fluor 647
NBP2-74113AF647
Alexa Fluor 700
NBP2-74113AF700
Alexa Fluor 750
NBP2-74113AF750
Allophycocyanin
NBP2-74113APC
Allophycocyanin/Cy7
NBP2-74113APCCY7
CoraFluor 1
NBP2-74113CL1
DyLight 350
NBP2-74113UV
DyLight 405
NBP2-74113V
DyLight 488
NBP2-74113G
DyLight 550
NBP2-74113R
DyLight 594
NBP2-74113DL594
DyLight 650
NBP2-74113C
DyLight 680
NBP2-74113FR
DyLight 755
NBP2-74113IR
FITC
NBP2-74113F
Janelia Fluor 525
NBP2-74113JF525
Janelia Fluor 585
NBP2-74113JF585
Janelia Fluor 635
NBP2-74113JF635
Janelia Fluor 646
NBP2-74113JF646
Janelia Fluor 669
NBP2-74113JF669
PE
NBP2-74113PE
PE/Atto594
NBP2-74113PEATT594
PE/Cy5.5
NBP2-74113PECY55
PE/Cy7
NBP2-74113PECY7
PerCP
NBP2-74113PCP
Unconjugated
NBP1-47964
mFluor Violet 450 SE
NBP2-74113MFV450
mFluor Violet 500 SE
NBP2-74113MFV500
mFluor Violet 610 SE
NBP2-74113MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP1-47964
Azide and BSA Free
NBP2-74113
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Serpin C1/Antithrombin-III Antibody (OTI8D5) [Janelia Fluor® 549] Summary

Immunogen
Full length recombinant protein of human Serpin C1/Antithrombin-III (NP_000479) produced in HEK293T cells.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
SERPINC1
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Serpin C1/Antithrombin-III Antibody (OTI8D5) [Janelia Fluor® 549]

  • Antithrombin-III
  • AT3antithrombin-III
  • ATIII
  • ATIIIantithrombin III
  • MGC22579
  • serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1
  • serine-cysteine proteinase inhibitor clade C member 1
  • Serpin C1
  • serpin peptidase inhibitor, clade C (antithrombin), member 1

Background

Antithrombin III (ATH III) is a plasma protein synthesised in the liver. Normal plasma levels are 115 to 160mg/L. ATH III consists of a single polypeptide chain and has a molecular weight of 58kDa. ATH III is a serine protease inhibitor and regulates coagulation by the formation of covalently liked complexes. ATH III also has a heparin binding site and in the presence of heparin the inhibition of thrombin, factors IXa, Xa and XIa is enhanced 1000 fold. Low levels of ATH III (functional or concentration) are associated with deep vein thrombosis and pulmonary embolism. Antithrombin assays are based on immunologic, enzymatic, or clotting properties

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Activator/tPA [HRP]
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Species: Hu
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Antibody - BSA Free
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Bioinformatics

Gene Symbol SERPINC1