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Serpin A7/TBG Antibody (001) [Janelia Fluor® 669]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications ELISA
Clone
001
Clonality
Monoclonal
Host
Rabbit
Conjugate
Janelia Fluor 669

Order Details

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Serpin A7/TBG Antibody (001) [Janelia Fluor® 669] Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Serpin A7/TBG (Accession#: NP_808588.3; Met 1-Gln 418).
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
SERPINA7
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Serpin A7/TBG Antibody (001) [Janelia Fluor® 669]

  • antitrypsin), member 7
  • FLJ17820
  • member 7
  • Serpin A7
  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin)
  • T4-binding globulin
  • TBG
  • TBGclade A (alpha-1 antiproteinase
  • thyroxin-binding globulin
  • thyroxine-binding globulin

Background

Thyroxine Binding Globulin (TBG) is one of three proteins responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3 triiodothyronine (T3) in the bloodstream, along with transthyretin and albumin. TBG has the highest affinity for T4 and T3, but is present in the lowest concentration of the three proteins. Despite its low concentration, TBG carries the majority of T4 in serum. Due to the very low serum concentration of T4 & T3, TBG is rarely more than 25% saturated with ligand. Unlike transthyretin and albumin, TBG has a single binding site for T4/T3. Genomically, TBG is a serpin, although it has no inhibitory function like many other members of this class of proteins. TBG is synthesized primarily in the liver.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol SERPINA7