S. frugiperda insect ovarian cell line Sf 21-derived recombinant mouse Semaphorin 6A Gly19-Thr649 Accession # O35464
Specificity
Detects mouse Semaphorin 6A in direct ELISAs and Western blots. In direct ELISAs, approximately 40% cross-reactivity with recombinant human (rh) Semaphorin 6A is observed and no cross-reactivity with recombinant mouse Semaphorins 3C, 3E, 3F or 7A, or rhSemaphorins 3A, or 3B is observed.
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Rat
Gene
SEMA6A
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Semaphorin 6A Antibody (201932)
KIAA1368HT018
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
Sema VIA
SEMA
Sema6A
SEMA6A1
SEMA6A-1
Semaphorin 6A
semaphorin 6A-1
Semaphorin VIA
semaphorin-6A
semaphorin-6A-1
SEMAQ
VIA
Background
Semaphorin 6A (Sema6A) is a member of the class 6 semaphorin
family of type I transmembrane proteins important in axon
guidance during neuronal development. Class 6 semaphorins mediate bidirectional
signaling, in part through interaction with plexin A1. In
addition to neuronal expression, Semaphorin 6A is induced by IFN-gamma in
Langerhans cells. Mature mouse and human Semaphorin 6A extracellular domains
share 95% amino acid sequence identity.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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