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ROR1 Antibody (zilovertamab) - Humanized

Images

 
Immobilized human ROR1 His at 2 ug/mL can bind ROR1 Antibody (zilovertamab) - Humanized, EC50=0.00283 ug/mL.
zilovertamab by Human ROR1 HEK293T cells increased with the increase of antibody concentration, and the Internalization Rate (%) reached 72%.
A549 cells were stained with ROR1 Antibody (zilovertamab) - Humanized and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC50=0.002776 ug/ml.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA, Flow, Func
Clone
zilovertamab
Clonality
Monoclonal
Host
Human
Conjugate
Unconjugated
Concentration
LYOPH

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ROR1 Antibody (zilovertamab) - Humanized Summary

Description
Expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 146.14 kDa.

Also known as 'zilovertamab'.

Upon receipt, store immediately at -20C or lower for 24 months in a lyophilized state. - 80C for 3 months after reconstitution. Avoid repeated freeze-thaw cycles.
Additional Information
Recombinant Monoclonal Antibody
Immunogen
ROR1
Isotype
IgG1
Clonality
Monoclonal
Host
Human
Gene
ROR1
Purity
Protein A purified
Endotoxin Note
< 0.001EU/ug,determined by LAL method.
Innovator's Reward
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Applications/Dilutions

Dilutions
  • ELISA
  • Flow Cytometry
  • Functional

Packaging, Storage & Formulations

Storage
Store at 4C.
Buffer
Lyophilized from 25mM histidine, 8% sucrose, 0.01% Tween80 (pH6.2)
Preservative
No Preservative
Concentration
LYOPH
Purity
Protein A purified
Reconstitution Instructions
Reconstitute with sterile, distilled water to a final concentration of 1 mg/ml. Gently shake to solubilize completely. Do not vortex.

Alternate Names for ROR1 Antibody (zilovertamab) - Humanized

  • EC 2.7.10.1
  • MGC99659
  • neurotrophic tyrosine kinase receptor-related 1
  • Neurotrophic tyrosine kinase, receptor-related 1
  • NTRKR1
  • NTRKR1dJ537F10.1
  • receptor tyrosine kinase-like orphan receptor 1
  • ROR1
  • tyrosine-protein kinase transmembrane receptor ROR1

Background

ROR1 is encoded by this gene is a receptor protein tyrosine kinase that modulates neurite growth in the central nervous system. It is a type I membrane protein and belongs to the ROR subfamily of cell surface receptors. Alternative splicing results in multiple transcript variants encoding different isoforms.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol ROR1
Uniprot